Evidence map›Paper›PMID 32390513›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats.

Bibek Poudel, Corbin A Shields, Andrea K Brown, Ubong Ekperikpe, Tyler Johnson, Denise C Cornelius, Jan M Williams

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. IL-33 Signaling Inhibition Leads to a Preeclampsia-Like Phenotype in Pregnant Rats.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024
    Article
  5. Article
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  8. Review
  9. Article
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  11. NLRP3 inhibition improves maternal hypertension, inflammation, and vascular dysfunction in response to placental ischemia.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  12. Neutralizing MIP3The Journal of pharmacology and experimental therapeutics · 2023
    Article
  13. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  14. The SSAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bibek PoudelDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Corbin A ShieldsDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Andrea K BrownDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Ubong EkperikpeDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Tyler JohnsonDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
Denise C CorneliusDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0002-6730-6499
Jan M WilliamsDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, Mississippi.
University of Mississippi Medical Center · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI Yufeng Zheng · 2012 to 2026
$60.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Mechanisms involved in the early development of renal disease associated with prepubertal obesityR01DK109133 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2017 to 2021
$1.7M
Hypertension and InflammationR00HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2017 to 2019
$747k
Hypertension and InflammationK99HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2016 to 2016
$136k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK109133HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM103476HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM104357HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM121334National Heart and Lung Institute (NHLI) HL130456NHLBI NIH HHS K99 HL130456NHLBI NIH HHS R00 HL130456NHLBI NIH HHS T32 HL105324NIDDK NIH HHS R01 DK109133NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

Recently, we reported that obese Dahl salt-sensitive (SS) leptin receptor mutant (SS

Indexed as

AnimalsBlood GlucoseCell ProliferationClodronic AcidDisease Models, AnimalDisease ProgressionFemaleFibrosisInsulinKidneyKidney DiseasesMacrophagesMaleMutationObesityRats, Inbred DahlBlood GlucoseClodronic AcidInsulinReceptors, LeptinTriglyceridesclodronateDahl salt-sensitive leptin receptor mutant strainmacrophagesobesityrenal diseasesalt-sensitive rat

Identifiers

PMID32390513
PMCPMC7311704
OpenAlexW3021569678

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.