Evidence map›Paper›PMID 32391739›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2020

Sex-dependent Regeneration Patterns in Mouse Submandibular Glands.

Callie T Brown, Kihoon Nam, Yue Zhang, Yuqing Qiu, Spencer M Dean, Harim T Dos Santos, Pedro Lei, Stelios T Andreadis, Olga J Baker

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Callie T BrownSchool of Dentistry, The University of Utah, Salt Lake City, Utah.
Kihoon NamSchool of Dentistry, The University of Utah, Salt Lake City, Utah.
Yue ZhangDepartment of Internal Medicine, Division of Epidemiology, The University of Utah, Salt Lake City, Utah.
Yuqing QiuDepartment of Internal Medicine, Division of Epidemiology, The University of Utah, Salt Lake City, Utah.
Spencer M DeanSchool of Dentistry, The University of Utah, Salt Lake City, Utah.
Harim T Dos SantosSchool of Dentistry, The University of Utah, Salt Lake City, Utah.
Pedro LeiDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York.
Stelios T AndreadisDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York.
Olga J BakerSchool of Dentistry, The University of Utah, Salt Lake City, Utah.
University of Utah · USUniversity at Buffalo, State University of New York · US

Funding

THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATIONR01DE022971 · NIDCR · UNIVERSITY OF UTAH · PI ANDREADIS, STELIOS T., BAKER, OLGA JULIANA · 2012 to 2025
$7.2M
NIDCR NIH HHS R01 DE022971
6 · The paper itself

Abstract

Our previous studies indicated that YIGSR-A99 peptides chemically conjugated to fibrin hydrogel (FH) and applied to wounded submandibular gland (SMG) in vivo, formed new organized salivary tissue, whereas wounded SMG treated with FH alone or in the absence of a scaffold showed disorganized collagen formation and poor tissue healing. While these studies indicated that damaged SMG grow and differentiate when treated with FH containing L1 peptide, they were performed only in female mice. However, there is a well-established sexual dimorphism present in mouse SMG (e.g., males develop well-differentiated granular convoluted tubules, but these structures are poorly developed in females) and little is known about how these sex differences influence wound healing events. Therefore, the goal of this study was to conduct comparative analyses of regeneration patterns in male and female mice using L

Indexed as

RegenerationSex CharacteristicsAnimalsCollagenFemaleFibrinHydrogelsMacrophagesMaleMiceNeovascularization, PhysiologicSalivaSubmandibular GlandWound HealingCollagenFibrinHydrogelsgender differencesmaterials scienceregenerationsalivasalivary physiology

Identifiers

PMID32391739
PMCPMC7226622
OpenAlexW3021013186

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.