Evidence map›Paper›PMID 32391979›Full record

SynthesisJournal of neuroimaging : official journal of the American Society of Neuroimaging2020

MR Intracranial Vessel Wall Imaging: A Systematic Review.

Jae W Song, Brianna F Moon, Morgan P Burke, Srikant Kamesh Iyer, Mark A Elliott, Haochang Shou, Steven R Messé, Scott E Kasner, Laurie A Loevner, Mitchell D Schnall and 3 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  6. Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Vessel wall MR imaging in neuroradiology.La Radiologia medica · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Vessel wall MR imaging of intracranial atherosclerosis.Cardiovascular diagnosis and therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jae W SongDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-3127-6427
Brianna F MoonDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA.
Morgan P BurkeDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Srikant Kamesh IyerDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Mark A ElliottDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Haochang ShouDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania School of Medicine, Philadelphia, PA.
Steven R MesséDepartment of Neurology, Hospital of University of Pennsylvania, Philadelphia, PA.
Scott E KasnerDepartment of Neurology, Hospital of University of Pennsylvania, Philadelphia, PA.
Laurie A LoevnerDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Mitchell D SchnallDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
John E KirschAthinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA.
Walter R WitscheyDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Zhaoyang FanDepartment of Biomedical Sciences, Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.

Funding

Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Longitudinal and quantitative MR plaque imaging for prediction of response to medical management in symptomatic intracranial atherosclerosisR01HL147355 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG · 2019 to 2023
$2.1M
NHLBI NIH HHS R01 HL137984NHLBI NIH HHS R01HL137984NHLBI NIH HHS R01 HL147355NHLBI NIH HHS R01HL147355NHLBI NIH HHS T32 HL007954
6 · The paper itself

Abstract

The purpose of this systematic review is to identify trends and extent of variability in intracranial vessel wall MR imaging (VWI) techniques and protocols. Although variability in selection of protocol design and pulse sequence type is known, data on what and how protocols vary are unknown. Three databases were searched to identify publications using intracranial VWI. Publications were screened by predetermined inclusion/exclusion criteria. Technical development publications were scored for completeness of reporting using a modified Nature Reporting Summary Guideline to assess reproducibility. From 2,431 articles, 122 met the inclusion criteria. Trends over the last 23 years (1995-2018) show increased use of 3-Tesla MR (P < .001) and 3D volumetric T1-weighted acquisitions (P < .001). Most (65%) clinical VWI publications report achieving a noninterpolated in-plane spatial resolution of ≤.55 mm. In the last decade, an increasing number of technical development (n = 20) and 7 Tesla (n = 12) publications have been published, focused on pulse sequence development, improving cerebrospinal fluid suppression, scan efficiency, and imaging ex vivo specimen for histologic validation. Mean Reporting Summary Score for the technical development publications was high (.87, range: .63-1.0) indicating strong scientific technical reproducibility. Innovative work continues to emerge to address implementation challenges. Gradual adoption into the research and scientific community was suggested by a shift in the name in the literature from "high-resolution MR" to "vessel wall imaging," specifying diagnostic intent. Insight into current practices and identifying the extent of technical variability in the literature will help to direct future clinical and technical efforts to address needs for implementation.

Indexed as

BrainHumansIntracranial ArteriosclerosisMagnetic Resonance AngiographyMagnetic Resonance ImagingReproducibility of Resultsintracranial atherosclerotic diseasemagnetic resonance imagingvasculopathyvessel wall MR imaging

Identifiers

PMID32391979
PMCPMC7946440

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.