Evidence map›Paper›PMID 32392822›Full record

ArticleGenes2020

Cellular Environment Remodels the Genomic Fabrics of Functional Pathways in Astrocytes.

Dumitru A Iacobas, Sanda Iacobas, Randy F Stout, David C Spray

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Special Issue "Molecules at Play in Neurological Diseases".Current issues in molecular biology · 2025
    Article
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  14. Powerful quantifiers for cancer transcriptomics.World journal of clinical oncology · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Dumitru A IacobasPersonalized Genomics Laboratory, Center for Computational Systems Biology, RG Perry College of Engineering, Prairie View A&M University, Prairie View, TX 77446, USA.ORCID 0000-0001-9700-6537
Sanda IacobasDepartment of Pathology, New York Medical College, Valhalla, NY 10595, USA.
Randy F StoutDepartment of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY 11568, USA.
David C SprayDP Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
Albert Einstein College of Medicine · USNew York Institute of Technology · USNew York Medical College · US

Funding

AQP4 isoforms and brain edemaR21NS116892 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI FRIGERI, ANTONIO, NICCHIA, GRAZIAPAOLA · 2020 to 2020
$472k
NIH HHS NS092466, NS092786NINDS NIH HHS R21 NS116892
6 · The paper itself

Abstract

We profiled the transcriptomes of primary mouse cortical astrocytes cultured alone or co-cultured with immortalized precursor oligodendrocytes (

Indexed as

TranscriptomeActin CytoskeletonAnimalsAstrocytesCell CommunicationCell CycleCells, CulturedCell ShapeCerebral CortexCircadian RhythmCoculture TechniquesCulture Media, ConditionedCytoskeletonGap JunctionsGene Expression RegulationGene OntologyCulture Media, Conditionedcalcium signalingchemokine signalingCx43gap junctionNOD-like receptor signalingoli-neu cellspannexin1PI3K-Akt pathwaythyroid hormone pathway

Identifiers

PMID32392822
PMCPMC7290327
OpenAlexW3021504721

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.