Evidence map›Paper›PMID 32394347›Full record

ArticleGeroScience2020

Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.

Kavithalakshmi Sataranatarajan, Gavin Pharaoh, Jacob L Brown, Rojina Ranjit, Katarzyna M Piekarz, Kaitlyn Street, Jonathan D Wren, Constantin Georgescu, Caroline Kinter, Michael Kinter and 3 more

Open access · greenAbstract read
In one paragraph

Article in GeroScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. iPLAScience advances · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Reactive oxygen species in the pathogenesis of sarcopenia.Free radical biology & medicine · 2025
    Review
  8. Article
  9. 5'-Cytimidine Monophosphate Ameliorates HAntioxidants (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Redox Signaling and Sarcopenia: Searching for the Primary Suspect.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Kavithalakshmi SataranatarajanAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Gavin PharaohAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Jacob L BrownAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Rojina RanjitAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Katarzyna M PiekarzAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Kaitlyn StreetAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Jonathan D WrenGenes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Constantin GeorgescuGenes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Caroline KinterAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Michael KinterAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Willard M FreemanGenes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Arlan RichardsonOklahoma Center for Geroscience, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Holly Van RemmenAging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA. holly-vanremmen@omrf.org.
Oklahoma Medical Research Foundation · USOklahoma City VA Medical Center · USUniversity of Oklahoma Health Sciences Center · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Michael T Kinter · 2012 to 2026
$60.2M
PROJECT 3: Neuromuscular redox homeostasis in mice lacking SOD1 and aging wild type mice subcontract at University of LiverpoolP01AG051442 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V · 2016 to 2020
$8.9M
Defining the relative roles of pre- and post-synaptic events in the initiation and progression of sarcopeniaR01AG050676 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V, VAN REMMEN, HOLLY · 2016 to 2020
$3.3M
NIA NIH HHS AG050676NIA NIH HHS AG051442NIA NIH HHS P01 AG051442NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

Mice lacking the superoxide anion scavenger CuZn superoxide dismutase (Sod1

Indexed as

SarcopeniaAnimalsMetabolic Networks and PathwaysMiceMuscle, SkeletalMuscular AtrophyOxidative StressAgingMuscle atrophyOxidative stressReactive oxygen species (ROS)SarcopeniaSod1 knockout mice

Identifiers

PMID32394347
PMCPMC7394980
OpenAlexW3024696408

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.