Evidence mapPaperPMID 32395481Full record

ArticleAnnals of translational medicine2020

Fazhong He, Bao Sun, Ling Li, Mouze Liu, Weijie Lin, Lin Liu, Yinxiang Sun, Yuhong Luo, Lin Wu, Ligong Lu and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Frontiers in genetics · 2022
    Article
  3. Tribbles pseudokinase 3 (Annals of translational medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Fazhong HeZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Bao SunDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410078, China.
Ling LiDepartment of Pharmacy, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China.
Mouze LiuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410078, China.
Weijie LinZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Lin LiuZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Yinxiang SunZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Yuhong LuoZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Lin WuDepartment II of Thoracic Medicine, Hunan Cancer Hospital, Changsha 519000, China.
Ligong LuZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Wei ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410078, China.
Zhiling ZhouZhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai 519000, China.
Jinan University · CNXiangya Hospital Central South University · CNFifth Affiliated Hospital of Sun Yat-sen University · CNHunan Cancer Hospital · CNZhuhai People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur previous studies have found that single nucleotide polymorphisms (SNPs) of

methodsA total of 830 hypertensive patients, who were administered with open-labeled hydrochlorothiazide (12.5 mg once daily) and randomly assigned to off-labeled felodipine (5 mg) or a matched placebo combination treatment (1:1), were selected from the Felodipine Event Reduction (FEVER) study. A strategy of screening 259 samples and validating the remaining 531 samples was implemented. Four functional SNPs were selected (rs2295490, rs11470129, rs4815567 and rs6037475 in

resultsWe found that

conclusionsThese results suggest that

Indexed as

felodipinehypertensionindividualized drug therapypharmacogeneticsTribbles homolog 3 (TRIB3)

Identifiers

PMID32395481
PMCPMC7210142
OpenAlexW3016032450

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.