Evidence map›Paper›PMID 32398861›Full record

ArticleCell research2020

Forks in the road to the first hematopoietic stem cells.

Elizabeth D Howell, Nancy A Speck

Abstract readComment
In one paragraph

Article in Cell research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Hematopoietic Stem Cell Development in Mammalian Embryos.Advances in experimental medicine and biology · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elizabeth D HowellDepartment of Cell and Developmental Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.
Nancy A SpeckDepartment of Cell and Developmental Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. nancyas@upenn.edu.ORCID http://orcid.org/0000-0002-1893-582X

Funding

Biochemistry of Leukemia Virus Core-Binding FactorR01HL091724 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SPECK, NANCY · 2008 to 2024
$8.3M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
BIOCHEMISTRY OF LEUKEMIA VIRUS CORE-BINDING FACTORR01CA058343 · NCI · DARTMOUTH COLLEGE · PI SPECK, NANCY ASMUSSEN · 1993 to 2007
$3.0M
Mechanisms of endothelial-to-hemogenic transition mediated by Runx1R01HD089245 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI SPECK, NANCY, TAN, KAI · 2017 to 2021
$2.1M
Identifying necessary chromatin states and targets for hemogenic specification and reprogrammingF31HL150952 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HOWELL, ELIZABETH · 2020 to 2021
$70k
NCI NIH HHS R01 CA058343NHLBI NIH HHS F31 HL150952NHLBI NIH HHS R01 HL091724NICHD NIH HHS R01 HD089245NICHD NIH HHS T32 HD083185
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic Stem CellsTranscriptomeDNA Replication

Identifiers

PMID32398861
PMCPMC7264252

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.