Evidence map›Paper›PMID 32403407›Full record

ArticleInternational journal of molecular sciences2020

Disease-Specific Derangement of Circulating Endocannabinoids and

Dorian Forte, Flaminia Fanelli, Marco Mezzullo, Martina Barone, Giulia Corradi, Giuseppe Auteri, Daniela Bartoletti, Marina Martello, Emanuela Ottaviani, Carolina Terragna and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Dorian ForteInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-8443-605X
Flaminia FanelliUnit of Endocrinology and Prevention and Care of Diabetes, Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, University-Hospital S.Orsola, 40138 Bologna, Italy.
Marco MezzulloUnit of Endocrinology and Prevention and Care of Diabetes, Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, University-Hospital S.Orsola, 40138 Bologna, Italy.
Martina BaroneInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Giulia CorradiInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Giuseppe AuteriInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Daniela BartolettiInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Marina MartelloInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Emanuela OttavianiInstitute of Hematology "L. e A. Seràgnoli", Department of Oncology and Hematology, University-Hospital S.Orsola, 40138 Bologna, Italy.
Carolina TerragnaInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Antonio CurtiInstitute of Hematology "L. e A. Seràgnoli", Department of Oncology and Hematology, University-Hospital S.Orsola, 40138 Bologna, Italy.
Uberto PagottoUnit of Endocrinology and Prevention and Care of Diabetes, Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, University-Hospital S.Orsola, 40138 Bologna, Italy.ORCID 0000-0003-4182-3110
Francesca PalandriInstitute of Hematology "L. e A. Seràgnoli", Department of Oncology and Hematology, University-Hospital S.Orsola, 40138 Bologna, Italy.
Michele CavoInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
Lucia CataniInstitute of Hematology "L. e A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine (DIMES), School of Medicine, University of Bologna, 40138 Bologna, Italy.
University of Bologna · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 20930SIE-Società Italiana di Ematologia- e Associazione "Amici di Beat Leukemia Dr. Alessandro Cevenini ONLUS /
6 · The paper itself

Abstract

Growing evidence highlights the endocannabinoid (EC) system involvement in cancer progression. Lipid mediators of this system are secreted by hematopoietic cells, including the ECs 2-arachidonoyl-glycerol (2AG) and arachidonoyl-ethanolamide (AEA), the 2AG metabolite 1AG, and members of N-acylethanolamine (NAE) family-palmitoyl-ethanolamide (PEA) and oleoyl-ethanolamide (OEA). However, the relevance of the EC system in myeloproliferative neoplasms (MPN) was never investigated. We explored the EC plasma profile in 55 MPN patients, including myelofibrosis (MF;

Indexed as

AdultAgedAged, 80 and overAmidesArachidonic AcidsChromatography, LiquidEndocannabinoidsEthanolaminesFemaleGlyceridesHumansJanus Kinase 2MaleMiddle AgedMutation, MissenseMyeloproliferative DisordersAmidesanandamideArachidonic AcidsEndocannabinoidsEthanolaminesGlyceridesglyceryl 2-arachidonateJAK2 protein, humanJanus Kinase 2N-acylethanolaminesOleic AcidsoleoylethanolamidepalmidrolPalmitic AcidsPolyunsaturated Alkamidesendocannabinoidsessential thrombocythemiamyelofibrosismyeloproliferative neoplasmsN-acylethanolaminespolycythemia vera

Identifiers

PMID32403407
PMCPMC7246996
OpenAlexW3023253756

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.