Evidence map›Paper›PMID 32406137›Full record

ArticleMagnetic resonance in medicine2020

Improved velocity-selective-inversion arterial spin labeling for cerebral blood flow mapping with 3D acquisition.

Dapeng Liu, Feng Xu, Wenbo Li, Peter C van Zijl, Doris D Lin, Qin Qin

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

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  16. TMagnetic resonance in medicine · 2022
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  18. HyperpolarizedMagnetic resonance in medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dapeng LiuThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-4432-3202
Feng XuThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wenbo LiThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0199-1534
Peter C van ZijlThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Doris D LinThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Qin QinThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6432-2944
Kennedy Krieger Institute · USJohns Hopkins University · US

Funding

TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2012 to 2020
$13.1M
Non-Contrast-Enhanced Velocity-Selective MR Angiography at 3T for Cerebrovascular DiseasesR01HL138182 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2018 to 2022
$2.0M
Velocity-Selective Arterial Spin Labeling based Perfusion Mapping for Cerebrovascular DiseasesR01HL144751 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2019 to 2022
$1.7M
NON-CONTRAST-ENHANCED PERIPHERAL MR ANGIOGRAPHYR01HL135500 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY, WILSON, DAVID LYNN · 2017 to 2020
$1.5M
MRI-based Quantitative Brain Perfusion Mapping for Sickle Cell DiseaseK25HL121192 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI QIN, QIN · 2014 to 2018
$822k
MRI-based Quantitative Brain Oximetry for Sickle Cell DiseaseK25HL145129 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LI, WENBO · 2019 to 2021
$457k
NHLBI NIH HHS K25 HL121192NHLBI NIH HHS K25 HL145129NHLBI NIH HHS R01 HL135500NHLBI NIH HHS R01 HL138182NHLBI NIH HHS R01 HL144751NIBIB NIH HHS P41 EB015909
6 · The paper itself

Abstract

purposeTo further optimize the velocity-selective arterial spin labeling (VSASL) sequence utilizing a Fourier-transform based velocity-selective inversion (FT-VSI) pulse train, and to evaluate its utility for 3D mapping of cerebral blood flow (CBF) with a gradient- and spin-echo (GRASE) readout.

methodsFirst, numerical simulations and phantom experiments were done to test the susceptibility to eddy currents and B

resultsThe simulations and phantom test showed that composite refocusing pulses are more robust to both eddy-currents and B

conclusionFT-VSI with 3D-GRASE readout was successfully implemented and showed higher sensitivity to perfusion signal than PCASL for both young and middle-aged healthy volunteers.

Indexed as

Cerebrovascular CirculationMagnetic Resonance AngiographyBrainHumansImaging, Three-DimensionalMiddle AgedSignal-To-Noise RatioSpin LabelsSpin Labels3D GRASE acquisitionarterial spin labelingcerebral blood flowvelocity-selective inversion

Identifiers

PMID32406137
PMCPMC7402012
OpenAlexW3026017147

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.