Evidence mapPaperPMID 32408626Full record

ArticleInternational journal of environmental research and public health2020

Initiation and Single Dispensing in Cardiovascular and Insulin Medications: Prevalence and Explanatory Factors.

Carles Vilaplana-Carnerero, Ignacio Aznar-Lou, María Teresa Peñarrubia-María, Antoni Serrano-Blanco, Rita Fernández-Vergel, Dolors Petitbò-Antúnez, Montserrat Gil-Girbau, Marian March-Pujol, Juan Manuel Mendive, Alba Sánchez-Viñas and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Carles Vilaplana-CarnereroResearch and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain.
Ignacio Aznar-LouResearch and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain.ORCID 0000-0002-6780-5968
María Teresa Peñarrubia-MaríaConsortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), 28029 Madrid, Spain.
Antoni Serrano-BlancoConsortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), 28029 Madrid, Spain.
Rita Fernández-VergelPrimary Care Research Institute (IDIAP Jordi Gol), 08007 Barcelona, Spain.
Dolors Petitbò-AntúnezCatalan Institute of Health, 08028 Barcelona, Spain.
Montserrat Gil-GirbauResearch and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain.
Marian March-PujolSchool of Pharmacy, University of Barcelona, 08028 Barcelona, Catalonia, Spain.
Juan Manuel MendivePrimary Care Research Institute (IDIAP Jordi Gol), 08007 Barcelona, Spain.
Alba Sánchez-ViñasResearch and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain.
Cristina Carbonell-DuacastellaResearch and Development Unit, Institut de Recerca Sant Joan de Déu, 08830 Barcelona, Catalonia, Spain.ORCID 0000-0002-8794-5490
Maria Rubio-ValeraConsortium for Biomedical Research in Epidemiology & Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), 28029 Madrid, Spain.
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESInstitut de Recerca Sant Joan de DéuInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESParc Sanitari Sant Joan de Déu · ESRed de Investigación en Actividades Preventivas y Promoción de la Salud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence problems have negative effects on health, but there is little information on the magnitude of non-initiation and single dispensing.

objectiveThe aim of this study was to estimate the prevalence of non-initiation and single dispensation and identify associated predictive factors for the main treatments prescribed in Primary Care (PC) for cardiovascular disease (CVD) and diabetes.

methodsCohort study with real-world data. Patients who received a first prescription (2013-2014) for insulins, platelet aggregation inhibitors, angiotensin-converting enzyme inhibitors (ACEI) or statins in Catalan PC were included. The prevalence of non-initiation and single dispensation was calculated. Factors that explained these behaviours were explored.

resultsAt three months, between 5.7% (ACEI) and 9.1% (antiplatelets) of patients did not initiate their treatment and between 10.6% (statins) and 18.4% (ACEI) filled a single prescription. Body mass index, previous CVD, place of origin and having a substitute prescriber, among others, influenced the risk of non-initiation and single dispensation.

conclusionsThe prevalence of non-initiation and single dispensation of CVD medications and insulin prescribed in PC in is high. Patient and health-system factors, such as place of origin and type of prescriber, should be taken into consideration when prescribing new medications for CVD and diabetes.

Indexed as

Cardiovascular AgentsCardiovascular DiseasesDiabetes MellitusHypoglycemic AgentsInsulinMedication AdherenceAgedAngiotensin-Converting Enzyme InhibitorsCohort StudiesFemaleHumansMaleMiddle AgedPrevalenceAngiotensin-Converting Enzyme InhibitorsCardiovascular AgentsHypoglycemic AgentsInsulinadherencecardiovascular diseasesinsulinmedication initiationprimary carereal-world data

Identifiers

PMID32408626
PMCPMC7277594
OpenAlexW3024029413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.