Evidence map›Paper›PMID 32412785›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2020

Matthew Perry Koppinger, Marissa Anne Lopez-Pier, Rinku Skaria, Preston Royal Harris, John P Konhilas

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021
    Guideline
  2. mBio · 2026
    Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Bioactive Constituents ofInternational journal of molecular sciences · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Matthew Perry KoppingerDepartment of Nutritional Sciences, University of Arizona, Tucson, Arizona.
Marissa Anne Lopez-PierDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona.ORCID 0000-0001-7692-0864
Rinku SkariaDepartment of Physiology, University of Arizona, Tucson, Arizona.
Preston Royal HarrisDepartment of Nutritional Sciences, University of Arizona, Tucson, Arizona.
John P KonhilasDepartment of Nutritional Sciences, University of Arizona, Tucson, Arizona.
University of Arizona · US

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Cardiovascular Biomedical Engineering Training GrantT32HL007955 · NHLBI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2001 to 2020
$5.1M
Impact of AMP-activated kinase on sex differences in hypertrophic cardiomyopathyR01HL098256 · NHLBI · UNIVERSITY OF ARIZONA · PI KONHILAS, JOHN P · 2010 to 2014
$1.9M
Metabolism, Skeletal Muscle, Cardiac Disease, ExerciseK01AR052840 · NIAMS · UNIVERSITY OF COLORADO · PI KONHILAS, JOHN P · 2006 to 2010
$600k
Impact of AMP-activated kinase on sex differences in hypertrophic cardiomyopathyK02HL105799 · NHLBI · UNIVERSITY OF ARIZONA · PI KONHILAS, JOHN P · 2011 to 2015
$516k
HHS | National Institutes of Health (NIH) GM004905HHS | National Institutes of Health (NIH) HL007249HHS | National Institutes of Health (NIH) HL00795515NHLBI NIH HHS K02 HL105799NHLBI NIH HHS R01 HL098256NHLBI NIH HHS T32 HL007249NHLBI NIH HHS T32 HL007955NIAMS NIH HHS K01 AR052840
6 · The paper itself

Abstract

Disruption of the normal gut microbiome (dysbiosis) is implicated in the progression and severity of myriad disorders, including hypercholesterolemia and cardiovascular disease. Probiotics attenuate and reverse gut dysbiosis to improve cardiovascular risk factors like hypertension and hypercholesterolemia.

Indexed as

AnimalsCholesterolGastrointestinal MicrobiomeLimosilactobacillus reuteriMaleMiceMice, Inbred C57BLMyocardial Reperfusion InjuryProbioticsReceptors, LDLCholesterolReceptors, LDLcholesterolgut microbiota, Lactobacillus reuterimyocardial infarctionprobiotics

Identifiers

PMID32412785
PMCPMC7474440
OpenAlexW3025915021

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.