Evidence map›Paper›PMID 32426239›Full record

ReviewToxicology reports2020

MicroRNAs and Xenobiotic Toxicity: An Overview.

Satheeswaran Balasubramanian, Kanmani Gunasekaran, Saranyadevi Sasidharan, Vignesh Jeyamanickavel Mathan, Ekambaram Perumal

Open access · goldAbstract readReview
In one paragraph

Review in Toxicology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Epigenetic Consequences of In Utero PFAS Exposure: Implications for Development and Long-Term Health.International journal of environmental research and public health · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Particulate matter-induced epigenetic modifications and lung complications.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  7. Review
  8. Breast Cancer Exposomics.Life (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Lipid carriers for mRNA delivery.Acta pharmaceutica Sinica. B · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Benzene Exposure and MicroRNAs Expression: In Vitro, In Vivo and Human Findings.International journal of environmental research and public health · 2023
    Review
  19. Article
  20. Functions of non-coding RNAs in regulating cancer drug targets.Acta biochimica et biophysica Sinica · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Satheeswaran BalasubramanianMolecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Kanmani GunasekaranMolecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Saranyadevi SasidharanMolecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Vignesh Jeyamanickavel MathanMolecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Ekambaram PerumalMolecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Bharathiar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of new technologies has paved the rise of various chemicals that are being employed in industrial as well as consumer products. This leads to the accumulation of these xenobiotic compounds in the environment where they pose a serious threat to both target and non-target species. miRNAs are one of the key epigenetic mechanisms that have been associated with toxicity by modulating the gene expression post-transcriptionally. Here, we provide a comprehensive view on miRNA biogenesis, their mechanism of action and, their possible role in xenobiotic toxicity. Further, we review the recent

Indexed as

ADAMTS9, A disintegrin and metalloproteinase with thrombospondin motifs 9Ag, SilverAHR, Aryl Hydrocarbon ReceptorAl2O3, Aluminium oxideAMPK, Adenosine Monophosphate-activated protein kinaseARRB1, Arrestin beta 1Au, GoldAβ, Amyloid BetaBaP, Benzo[a]pyreneBCB, Blood-cerebrospinal fluid barrierbcl2l11, B-cell lymphoma-2-like protein 11BiomarkersBNIP3−3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3CCNB1, Cyclin B1CDC25A, M-phase inducer phosphatase 1CDC25C, M-phase inducer phosphatase 3CDK1, Cyclin-dependent kinase 1CDK6, Cyclin-dependent kinase 6CDK, Cyclin-dependent KinaseCDKN1b, Cyclin-dependent kinase Inhibitor 1BCEC, Contaminants of Emerging ConcernceRNA, Competing endogenous RNACOPD, Chronic obstructive pulmonary diseaseCOX2, Cyclooxygenase-2CTGF, Connective Tissue Growth FactorDGCR8, DiGeorge syndrome chromosomal [or critical] region 8DNA, Deoxy ribonucleic acidDON, DeoxynivalenolEnvironmentEpigeneticsER, Endoplasmic ReticulumFadd, Fas-associated protein with death domainGene regulationGrp78/BIP, Binding immunoglobulin proteinGTP, Guanosine triphosphateHpf, Hours post fertilizationHSPA1A, Heat shock 70 kDa protein 1IL1R1, Interleukin 1 receptor, type 1IL-6, Interleukin 6LIN28B, Lin-28 homolog BlncRNAs, Long non-coding RNALRP-1-, Low density lipoprotein receptor-related protein 1MAPK, Mitogen Activated Protein KinaseMC-LR, Microcystin-Leucine ArginineMC-RR, Microcystin-Arginine ArgininemiRNA, MicroRNAMn, ManganeseMRE, MicroRNA Response ElementsmRNA, Messenger RNANASH, Non-alcoholic steatohepatitisNET1, Neuroepithelial Cell Transforming 1NFKBAP, NFKB Activating protein-1NF- ҡB, Nuclear Factor kappa-light-chain-enhancer of activated B cellsNMDAR, N-methyl-d-aspartate receptorNon-coding RNAsNPs, NanoparticlesNrf2, Nuclear factor erythroid 2-related factor 2PDCD4, Programmed cell death protein 4PFAS, Poly-fluoroalkyl substancesPM2.5, Particulate Matter2.5qRT-PCR, quantitative Real Time-Polymerase Chain Reactionripk 1, Receptor-interacting serine/threonine-protein kinase 1RISC, RNA-induced silencing complexRNAi, RNA interferenceRNA, Ribonucleic acidRNase III, Ribonuclease IIISEMA6D, Semaphorin-6DSiO2, Silicon dioxideSOLiD, Sequencing by Oligonucleotide Ligation and DetectionSPIONs, Superparamagnetic Iron Oxide NanoparticlesTCDD, 2,3,7,8-TetrachlorodibenzodioxinTNF-α, Tumor necrosis factor – alphaToxicityTP53, Tumor protein 53TRBP, Transactivation Response RNA Binding ProteinUTR, Untranslated regionWHO, World Health OrganizationWnt, Wingless-related integration siteZEA, ZearalanoneZn, Zinc

Identifiers

PMID32426239
PMCPMC7225592
OpenAlexW3021751495

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.