Evidence map›Paper›PMID 32432055›Full record

ArticleFrontiers in cellular and infection microbiology2020

Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways.

Chun-Xia Shi, Yao Wang, Qian Chen, Fang-Zhou Jiao, Mao-Hua Pei, Zuo-Jiong Gong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. NOD2-NLRP3 Axis and Asthma.Journal of asthma and allergy · 2025
    Review
  7. Review
  8. Review
  9. The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
  10. The role of extracellular histones in COVID-19.Journal of internal medicine · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chun-Xia ShiDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Yao WangDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Qian ChenDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Fang-Zhou JiaoDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Mao-Hua PeiDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Zuo-Jiong GongDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HistonesNLR Family, Pyrin Domain-Containing 3 ProteinNod2 Signaling Adaptor ProteinPyroptosisSepsisAnimalsCaspase 1InflammasomesMiceReceptors, ComplementCaspase 1HistonesInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseNod2 protein, mouseNod2 Signaling Adaptor ProteinReceptors, ComplementVSIG4 protein, mousehistone H3NOD2pyroptosissepsisVSIG4

Identifiers

PMID32432055
PMCPMC7216582
OpenAlexW3022847241

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.