Evidence map›Paper›PMID 32437891›Full record

ReviewFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2020

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence.

Aristidis Tsatsakis, Demetrious Petrakis, Taxiarchis Konstantinos Nikolouzakis, Anca Oana Docea, Daniela Calina, Marco Vinceti, Marina Goumenou, Ronald N Kostoff, Charalampos Mamoulakis, Michael Aschner and 1 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. The concentrations of essential/toxic elements in serum of COVID-19 patients are not directly related to the severity of the disease.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Article
  9. Article
  10. Global Human Threat: The Potential Synergism between Mercury Intoxication and COVID-19.International journal of environmental research and public health · 2023
    Article
  11. Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. An assessment of vaping-induced inflammation and toxicity: A feasibility study using a 2-stage zebrafish and mouse platform.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Article
  18. Review
  19. The "One Health" approach in the face of Covid-19: how radical should it be?Philosophy, ethics, and humanities in medicine : PEHM · 2022
    Review
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Aristidis TsatsakisLaboratory of Toxicology, Medical School, University of Crete, Voutes, 71409 Heraklion, Crete, Greece; Department of Analytical and Forensic Medical Toxicology, Sechenov University, 2-4 Bolshaya Pirogovskaya st., 119991 Moscow, Russia; Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York, NY 10461, USA. Electronic address: tsatsaka@uoc.gr.
Demetrious PetrakisLaboratory of Toxicology, Medical School, University of Crete, Voutes, 71409 Heraklion, Crete, Greece. Electronic address: dimitriospetrakis@hotmail.com.
Taxiarchis Konstantinos NikolouzakisLaboratory of Toxicology, Medical School, University of Crete, Voutes, 71409 Heraklion, Crete, Greece. Electronic address: konstan10@hotmail.gr.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. Electronic address: ancadocea@gmail.com.
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania. Electronic address: calinadaniela@gmail.com.
Marco VincetiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, I-41125 Modena, Italy. Electronic address: marco.vinceti@unimore.it.
Marina GoumenouLaboratory of Toxicology, Medical School, University of Crete, Voutes, 71409 Heraklion, Crete, Greece.
Ronald N KostoffSchool of Public Policy, Georgia Institute of Technology, Gainesville, VA, 20155, USA. Electronic address: rkostoff@gmail.com.
Charalampos MamoulakisDepartment of Urology, University General Hospital of Heraklion, Medical School, University of Crete, 71003 Heraklion, Crete, Greece. Electronic address: mamoulak@uoc.gr.
Michael AschnerDepartment of Analytical and Forensic Medical Toxicology, Sechenov University, 2-4 Bolshaya Pirogovskaya st., 119991 Moscow, Russia; Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York, NY 10461, USA. Electronic address: michael.Aschner@einstein.yu.edu.
Antonio F HernándezDepartment of Legal Medicine and Toxicology, University of Granada School of Medicine, 180016 Granada, Spain. Electronic address: ajerez@ugr.es.
University of Crete · GRUniversity of Medicine and Pharmacy of Craiova · ROAlbert Einstein College of Medicine · USGeorgia Institute of Technology · USUniversidad de Granada · ESUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occupational, residential, dietary and environmental exposures to mixtures of synthetic anthropogenic chemicals after World War II have a strong relationship with the increase of chronic diseases, health cost and environmental pollution. The link between environment and immunity is particularly intriguing as it is known that chemicals and drugs can cause immunotoxicity (e.g., allergies and autoimmune diseases). In this review, we emphasize the relationship between long-term exposure to xenobiotic mixtures and immune deficiency inherent to chronic diseases and epidemics/pandemics. We also address the immunotoxicologic risk of vulnerable groups, taking into account biochemical and biophysical properties of SARS-CoV-2 and its immunopathological implications. We particularly underline the common mechanisms by which xenobiotics and SARS-CoV-2 act at the cellular and molecular level. We discuss how long-term exposure to thousand chemicals in mixtures, mostly fossil fuel derivatives, exposure toparticle matters, metals, ultraviolet (UV)-B radiation, ionizing radiation and lifestyle contribute to immunodeficiency observed in the contemporary pandemic, such as COVID-19, and thus threaten global public health, human prosperity and achievements, and global economy. Finally, we propose metrics which are needed to address the diverse health effects of anthropogenic COVID-19 crisis at present and those required to prevent similar future pandemics.

Indexed as

BetacoronavirusAir PollutantsAnimalsAntiviral AgentsCoronavirus InfectionsCOVID-19DietEpidemicsHumansImmune SystemPandemicsPesticidesPneumonia, ViralPrevalenceReceptors, Aryl HydrocarbonRisk FactorsAir PollutantsAntiviral AgentsPesticidesReceptors, Aryl HydrocarbonXenobioticsChronic diseasesCoronavirusCOVID-19EpidemicImmune deficiencyPandemicPollutantsSARS-CoV-2Xenobiotics

Identifiers

PMID32437891
PMCPMC7211730
OpenAlexW3024477807

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.