Evidence map›Paper›PMID 32440483›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder.

Jia-Wei Guo, Xiu Liu, Ting-Ting Zhang, Xiao-Chun Lin, Yu Hong, Jie Yu, Qin-Yan Wu, Fei-Ran Zhang, Qian-Qian Wu, Jin-Yan Shang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Time-Restricted Feeding With High-Fat Diet Slows Weight Gain and Reduces Renal Calcium Oxalate Crystal Formation Without Reducing Energy Intake.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  2. Review
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  4. The function of chloride channels in digestive system disease (Review).International journal of molecular medicine · 2025
    Review
  5. TMAO promotes disorders of lipid metabolism in psoriasis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. The role of anoctamin 1 in liver disease.Journal of cellular and molecular medicine · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The diverse roles of TMEM16A CaJournal of advanced research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Jia-Wei GuoDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Xiu LiuDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Ting-Ting ZhangDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Xiao-Chun LinDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Yu HongDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Jie YuDepartment of Gastrointestinal Surgery The First Affiliated Hospital Sun Yat-Sen University Guangzhou 510080 China.
Qin-Yan WuDepartment of Gastroenterology The First People's Hospital of Foshan Foshan 528000 China.
Fei-Ran ZhangDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Qian-Qian WuKey Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission Ningxia Medical University Yinchuan 750004 China.
Jin-Yan ShangDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Xiao-Fei LvDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Jing-Song OuDivision of Cardiac Surgery The Key Laboratory of Assisted Circulation Ministry of Health The First Affiliated Hospital Sun Yat-Sen University Guangzhou 510080 China.
Jia-Guo ZhouDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Rui-Ping PangGuangdong Province Key Laboratory of Brain Function and Disease Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.
Bao-Dong TangDepartment of Gastroenterology The First Affiliated Hospital Sun Yat-Sen University Guangzhou 510080 China.
Si-Jia LiangDepartment of Pharmacology Cardiac and Cerebral Vascular Research Center Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China.ORCID https://orcid.org/0000-0002-4014-6325
Sun Yat-sen University · CNFirst People's Hospital of Foshan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease, and the mechanisms underpinning its pathogenesis have not been completely established. Transmembrane member 16A (TMEM16A), a component of the Ca

Indexed as

glucose metabolic disorderGLUT2hepatic steatosisnonalcoholic fatty liver diseaseTMEM16AVAMP3

Identifiers

PMID32440483
PMCPMC7237841
OpenAlexW3011848203

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.