Evidence mapPaperPMID 32444690Full record

Observational studyScientific reports2020

Histological grading evaluation of non-alcoholic fatty liver disease after bariatric surgery: a retrospective and longitudinal observational cohort study.

Felipe David Mendonça Chaim, Lívia Bitencourt Pascoal, Fábio Henrique Mendonça Chaim, Bruna Biazon Palma, Tiago Andrade Damázio, Larissa Bastos Eloy da Costa, Rita Carvalho, Everton Cazzo, Martinho Antônio Gestic, Murillo Pimentel Utrini and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Comparative effectiveness of medical treatmentHepatobiliary surgery and nutrition · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Observational
  15. Diabetic fibrosis.Biochimica et biophysica acta. Molecular basis of disease · 2021
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Felipe David Mendonça Chaim *Department of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Lívia Bitencourt Pascoal *IBD Research Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Fábio Henrique Mendonça ChaimDepartment of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Bruna Biazon PalmaIBD Research Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Tiago Andrade DamázioIBD Research Laboratory, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Larissa Bastos Eloy da CostaDepartment of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Rita CarvalhoDepartment of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Everton CazzoDepartment of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Martinho Antônio GesticDepartment of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Murillo Pimentel UtriniDepartment of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Marciane MilanskiLaboratory of Metabolic Disorders, School of Applied Sciences, University of Campinas (UNICAMP), Limeira, Brazil.
Elinton Adami Chaim *Department of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Raquel Franco Leal *Department of Surgery, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil. rafranco.unicamp@gmail.com.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a chronic disease with several degrees of histological features which may progress to cirrhosis. Obesity is an important risk factor and although NAFLD has no specific pharmacological treatment, bariatric surgery has been associated with NAFLD regression in severely obese patients. However, few longitudinal histological studies support this finding. Therefore, firstly, a retrospective study was performed including clinical and histological data of 895 obese patients who underwent bariatric surgery. In addition, histological analyses of 30 patient's liver biopsies were evaluated at two timepoints (T1 and T2). The retrospective analysis of the total number of patients revealed that the average body mass index (BMI) was 35.91 ± 2.81 kg/m

Indexed as

AdultAgedBariatric SurgeryBiomarkersBrazilCollagenCross-Sectional StudiesFemaleFollow-Up StudiesHumansLiverLiver Function TestsLongitudinal StudiesMacrophagesMaleMiddle AgedBiomarkersCollagen

Identifiers

PMID32444690
PMCPMC7244764
OpenAlexW3027200823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.