Evidence map›Paper›PMID 32456148›Full record

ArticleInternational journal of molecular sciences2020

Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones.

Vera M S Isca, Milan Sencanski, Nenad Filipovic, Daniel J V A Dos Santos, Ana Čipak Gašparović, Lucília Saraíva, Carlos A M Afonso, Patrícia Rijo, Alfonso T García-Sosa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Preliminary Biological Activity Screening ofPharmaceuticals (Basel, Switzerland) · 2021
    Article
  6. Frontiers in pharmacology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Vera M S IscaCenter for Research in Biosciences & Health Technologies (CBIOS), Universidade Lusófona de Humanidades e Tecnologias, 1749-024 Lisboa, Portugal.ORCID 0000-0002-9045-7287
Milan SencanskiLaboratory for Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences VINCA, University of Belgrade, P.O. Box 522, 11001 Belgrade, Serbia.
Nenad FilipovicDepartment of Chemistry and Biochemistry, Faculty of Agriculture, University of Belgrade, 11001 Belgrade, Serbia.ORCID 0000-0003-2982-5324
Daniel J V A Dos SantosInstituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisboa, Portugal.
Ana Čipak GašparovićRudjer Boskovic Institute, Bijenicka 54, HR-10000 Zagreb, Croatia.ORCID 0000-0003-2000-8950
Lucília SaraívaLAQV/REQUIMTE, Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira n.º 228, 4050-313 Porto, Portugal.ORCID 0000-0002-9531-4939
Carlos A M AfonsoInstituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisboa, Portugal.ORCID 0000-0002-7284-5948
Patrícia RijoCenter for Research in Biosciences & Health Technologies (CBIOS), Universidade Lusófona de Humanidades e Tecnologias, 1749-024 Lisboa, Portugal.ORCID 0000-0001-7992-8343
Alfonso T García-SosaInstitute of Chemistry, University of Tartu, Ravila 14a, 54011 Tartu, Estonia.ORCID 0000-0003-0542-4446
University of Lisbon · PTUniversity of Belgrade · RSRuđer Bošković Institute · HRUniversidade do Porto · PTUniversity of Tartu · EE

Funding

European Regional Development Fund POCI/01/0145/FEDER/007728Fundação para a Ciência e a Tecnologia PT2020 UID/MULTI/04378/2013 and the project (3599-PPCDT) PTDC/DTP-FTO/1981/2014 - POCI-01-0145-FEDER-016581Fundação para a Ciência e a Tecnologia UID/DTP/04567/2019, UID/QUI/50006/2020 and grants CBIOS/PRUID/BI1/2017 and SFRH/BD/137671/2018.Haridus- ja Teadusministeerium IUT34-14Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja 173001
6 · The paper itself

Abstract

Plants have been used for centuries to treat several illnesses. The

Indexed as

AbietanesAntineoplastic AgentsBinding SitesHumansIsoenzymesMCF-7 CellsMolecular Docking SimulationProtein BindingProtein Kinase CAbietanesAntineoplastic AgentsIsoenzymesProtein Kinase Croyleanonehemi-synthesisisozyme-selectivitymolecular interactionsPKC activityPlectranthusroyleanones

Identifiers

PMID32456148
PMCPMC7279380
OpenAlexW3028210043

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.