ArticleeLife2020
Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- NOTCH3 disrupts the osteoblast transcriptome in femoral bone of 1-month-old male C57BL/6 mice.Bone · 2026Article
- JAK-STAT signaling: molecular mechanism and targeted treatment in dento-maxillofacial abnormalities.International journal of oral science · 2026Review
- Role of Notch signaling in corticalization.Journal of endocrinological investigation · 2026Review
- Bone marrow neutrophil progenitors suppress osteoclast formation in murine cortical and trabecular bone.Blood · 2025Article
- Article
- Preclinical Rodent Models for Human Bone Disease, Including a Focus on Cortical Bone.Endocrine reviews · 2024Review
- Aging impairs the osteocytic regulation of collagen integrity and bone quality.Bone research · 2024Article
- Article
- Gut microbiome depletion and repetitive mild traumatic brain injury differentially modify bone development in male and female adolescent rats.Bone reports · 2021Article
- Cortical bone development, maintenance and porosity: genetic alterations in humans and mice influencing chondrocytes, osteoclasts, osteoblasts and osteocytes.Cellular and molecular life sciences : CMLS · 2021Review
- Exosome-Derived MicroRNAs of Human Milk and Their Effects on Infant Health and Development.Biomolecules · 2021Review
- Bone Geometry Is Altered by Follistatin-Induced Muscle Growth in Young Adult Male Mice.JBMR plus · 2021Article
- Measuring Bone Volume at Multiple Densities by Micro-computed Tomography.Bio-protocol · 2021Article
- [Observation of dendrite osteocytes of mice at different developmental stages using Ploton silver staining and phalloidin staining].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- The JAK1/STAT3/SOCS3 axis in bone development, physiology, and pathology.Experimental & molecular medicine · 2020Review
- Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling.The Journal of biological chemistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Bone strength is determined by its dense cortical shell, generated by unknown mechanisms. Here we use the
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.