Evidence map›Paper›PMID 32463592›Full record

ArticleJournal of cellular and molecular medicine2020

CFTR promotes malignant glioma development via up-regulation of Akt/Bcl2-mediated anti-apoptosis pathway.

Mingyue Zhao, Jieting Zhang, Wenqing Huang, Jianda Dong, Jinghui Guo, Kin Pong U, ZhiHui Weng, Si Liu, Hsiao Chang Chan, Hua Feng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression.Frontiers in cell and developmental biology · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Mingyue ZhaoDepartment of Neurosurgery, Airforce General Hospital of the PLA, Beijing, China.
Jieting ZhangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Wenqing HuangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Jianda DongDepartment of Pathology, Ningxia Medical University, Yinchuan, China.
Jinghui GuoEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Kin Pong UEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-2699-2776
ZhiHui WengEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Si LiuEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hsiao Chang ChanEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hua FengDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Xiaohua JiangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-7372-4961
Chinese University of Hong Kong · HKArmy Medical University · CNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-activated Cl

Indexed as

Signal TransductionAnimalsApoptosisCell Line, TumorCell ProliferationCystic Fibrosis Transmembrane Conductance RegulatorDisease ProgressionGene Expression Regulation, NeoplasticGliomaHumansMaleMice, NudeProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-bcl-2Up-RegulationCystic Fibrosis Transmembrane Conductance RegulatorProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-bcl-2AktapoptosisBcl2CFTRglioma

Identifiers

PMID32463592
PMCPMC7339181
OpenAlexW3031501358

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.