ArticleNutrients2020
Lifestyle and Progression to Type 2 Diabetes in a Cohort of Workers with Prediabetes.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Intervening Early in the Cardiovascular-Kidney-Metabolic Syndrome: Expert Recommendations from the United Arab Emirates on the Management of Prediabetes.Vascular health and risk management · 2026Guideline
- Risk factors for progression to type 2 diabetes in prediabetes: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Effect of physical activity and different exercise modalities on glycemic control in people with prediabetes: a systematic review and meta-analysis of randomized controlled trials.Frontiers in endocrinology · 2023Pooled it
- Influence of Social Determinants of Health on Adherence to Lifestyle Modifications in Individuals With Prediabetes: A Mixed Methods Study.Journal of advanced nursing · 2026Trial
- Understanding barriers and facilitators of adherence to lifestyle changes in prediabetes: a qualitative study.International journal of qualitative studies on health and well-being · 2026Observational
- Real-world predictors of progression to type 2 diabetes among adults with prediabetes.Diabetes, obesity & metabolism · 2026Article
- Effects of exercise based on ACSM recommendations on individuals with a prediabetic state: a systematic review and meta-analysis of randomised controlled trials.Endocrine connections · 2026Article
- Artificial intelligence in prediabetes care: applications in screening, risk prediction, and lifestyle intervention.Frontiers in endocrinology · 2026Review
- Epidemiological features and prevalence patterns of prediabetes outcomes in an east coast Malaysian cohort: A retrospective cohort study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026Article
- Predicting pre-diabetes progression: a systematic review and meta-analysis.BMJ nutrition, prevention & health · 2026Article
- Identifying Cardio-Metabolic Subtypes of Prediabetes Using Latent Class Analysis.Medical sciences (Basel, Switzerland) · 2025Article
- Article
- Fatty acids and physical activity are critical for β-cell mass and insulin sensitivity: Pathways to T2D and prevention.Journal of theoretical biology · 2025Article
- Incidence and predictors of type 2 diabetes mellitus in a population-based cohort study in Abu Dhabi.Scientific reports · 2025Article
- Use of technology in prediabetes and precision prevention.Journal of diabetes investigation · 2025Review
- Factors related to reversal of prediabetes in patients from a cardiovascular risk program during 2019 - 2023.Cardiovascular diabetology. Endocrinology reports · 2025Article
- Article
- Machine Learning Models Integrating Dietary Indicators Improve the Prediction of Progression from Prediabetes to Type 2 Diabetes Mellitus.Nutrients · 2025Article
- The De Ritis ratio mediates the association between creatinine-to-body weight ratio and normoglycemic conversion in Chinese health examinees.Scientific reports · 2025Article
- Article
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6 authors.
Funding
Abstract
backgroundPeople with prediabetes have an increased risk of developing type 2 diabetes (T2D). Few studies have evaluated the influence of lifestyle factors on the risk of progression to diabetes and reversion to normoglycemia. The aim of this study was to determine the incidence of T2D in a large cohort of workers with prediabetes, and to evaluate the influence of sociodemographic, clinical, metabolic, and lifestyle factors that affect the persistence of prediabetes and the progression to T2D.
methodsA cohort study of 27,844 adult workers (aged 20 to 65 years) from Spain who had prediabetes based on an occupational medical examination from 2012 to 2013. Prediabetes was defined as fasting plasma glucose (FPG) between 100 and 125 mg/dL. At the baseline evaluation, sociodemographic, anthropometric, metabolic, and lifestyle data were collected. At the 5-year follow-up, incident T2D was defined as an FPG of at least 126 mg/dL or initiation of an antidiabetic medication.
resultsAmong 235,995 initially screened workers, the prevalence of T2D was 14.19% (95% confidence interval (CI) 14.05 to 14.33) and the prevalence of prediabetes was 11.85% (95% CI 11.71 to 11.99). Follow-up data were available for 23,293 individuals with prediabetes. Among them, 36.08% (95% CI 35.46 to 36.70) returned to normoglycemia, 40.92% (95% CI 40.29 to 41.55) had persistent prediabetes, and 23.00% (95% CI 22.46 to 23.54) progressed to T2D. The risk for persistence of prediabetes and for progression to T2D increased with age, body mass index (BMI), triglyceride level, and less than 150 min/week of physical activity. An HbA1c level of 6% or greater was the strongest individual predictor of progression to T2D.
conclusionsPhysical activity, diet, smoking, and BMI are modifiable factors that are associated with the persistence of prediabetes and the progression to T2D. The workplace is a feasible setting for the early detection of prediabetes and the promotion of lifestyles that can prevent progression to T2D.
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