Evidence map›Paper›PMID 32471155›Full record

ArticleInternational journal of molecular sciences2020

Bioinformatic Analysis Reveals Phosphodiesterase 4D-Interacting Protein as a Key Frontal Cortex Dementia Switch Gene.

Judith A Potashkin, Virginie Bottero, Jose A Santiago, James P Quinn

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pan-cancer analysis of theOpen medicine (Warsaw, Poland) · 2023
    Article
  5. Physical Activity Rewires the Human Brain against Neurodegeneration.International journal of molecular sciences · 2022
    Article
  6. Article
  7. Article
  8. Functional Genomics in Health and Disease.International journal of molecular sciences · 2021
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Judith A PotashkinCenter for Neurodegenerative Diseases and Therapeutics, Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064 USA.
Virginie BotteroCenter for Neurodegenerative Diseases and Therapeutics, Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064 USA.
Jose A SantiagoNeuroHub Analytics, LLC, Chicago, IL 60605, USA.
James P QuinnQ Regulating Systems, LLC, Gurnee, IL 60031, USA.
Rosalind Franklin University of Medicine and Science · USQuality Systems (United States) · US

Funding

Network analysis for identifying disease mechanisms and therapeutic targets for dementiaR01AG062176 · NIA · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI POTASHKIN, JUDITH ANN · 2018 to 2019
$624k
NIA NIH HHS R01 AG062176NIH HHS R01AG062176
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Computational BiologyGenes, SwitchAdaptor Proteins, Signal TransducingAlzheimer DiseaseBrainCytoskeletal ProteinsDatabases, GeneticData MiningDementiaDementia, VascularFrontal LobeFrontotemporal DementiaGene Expression RegulationHumansSignal TransductionSoftwareAdaptor Proteins, Signal TransducingCytoskeletal ProteinsPDE4DIP protein, humanTranscription FactorsAlzheimer’s diseasebioinformatic analysiscardiomyopathy-associated protein 2Dementiafrontotemporal dementiagene expressioninflammationmyomegalinpersonalized medicinephosphodiesterase 4D-interacting proteinPI3K-AKT pathwayswitch genesubiquitin mediated proteinvalproic acidvascular dementia

Identifiers

PMID32471155
PMCPMC7313474
OpenAlexW3029623223

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.