ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2021
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04682483 (Cardiogenic Shock Working Group Registry), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiogenic Shock Working Group Registry
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Resource utilization associated with extracorporeal membrane oxygenation vs. microaxial flow pump for infarct-related cardiogenic shock.European heart journal. Acute cardiovascular care · 2025Pooled it
- Effects and safety of extracorporeal membrane oxygenation in the treatment of patients with ST-segment elevation myocardial infarction and cardiogenic shock: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Factors associated with native heart survival and intermediate-term outcomes in acute myocardial infarction-related cardiogenic shock.European heart journal open · 2026Article
- The Role of Impella in Cardiogenic Shock in the Post-DanGer Shock Era.Biomedicines · 2025Review
- Temporary Mechanical Support in Cardiogenic Shock Secondary to Heart Failure: An Evolving Paradigm.Journal of personalized medicine · 2025Review
- Blueprint for Building and Sustaining a Cardiogenic Shock Program: Qualitative Survey of 12 US Programs.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Best practices for vascular arterial access and closure: a contemporary guide for the cardiac catheterization laboratory.Frontiers in cardiovascular medicine · 2024Review
- An Uneven Playing Field: Demographic and Regionalized Disparities in Access to Device-Based Therapies for Cardiogenic Shock.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Immediate in-hospital outcomes after percutaneous revascularization of acute myocardial infarction complicated by cardiogenic shock.World journal of cardiology · 2023Article
- Prevention and management of critical care complications in cardiogenic shock: a narrative review.Journal of intensive care · 2023Review
- Impella Versus VA-ECMO for Patients with Cardiogenic Shock: Comprehensive Systematic Literature Review and Meta-Analyses.Journal of cardiovascular development and disease · 2023Review
- Incidence and predictors of acute limb ischemia in acute myocardial infarction complicated by cardiogenic shock.Journal of vascular surgery · 2023Observational
- Risk factors for percutaneous left ventricular assist device explant complications.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2023Article
- What is known in pre-, peri-, and post-procedural anticoagulation in micro-axial flow pump protected percutaneous coronary intervention?European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- Position Statement on Vascular Access Safety for Percutaneous Devices in AMI Complicated by Cardiogenic Shock.JACC. Cardiovascular interventions · 2022Review
- Save the Leg: Utilization of Distal Perfusion Catheter With Impella CP® May Prevent Morbidity of Limb.Cureus · 2022Article
- Contemporary Management of Cardiogenic Shock: A RAND Appropriateness Panel Approach.Circulation. Heart failure · 2021Article
- The science of safety: complications associated with the use of mechanical circulatory support in cardiogenic shock and best practices to maximize safety.F1000Research · 2020Review
- Article
- Design and Rationale of the Safe Surveillance of PCI Under Mechanical Circulatory Support With the Saranas Early Bird Bleed Monitoring System (SAFE-MCS) Study.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundBleeding complications and acute limb ischemia (ALI) are devastating vascular complications in patients with ST-segment elevation myocardial infarction (STEMI). Cardiogenic shock (CS) can further increase this risk due to multiorgan failure. In the contemporary era, percutaneous mechanical circulatory support is commonly used for management of CS. We hypothesized that vascular complications may be an important determinant of clinical outcomes for CS due to STEMI (CS-STEMI).
objectiveWe evaluated 10-year national trends, resource utilization and outcomes of bleeding complications, and ALI in CS-STEMI.
methodsWe performed a retrospective cohort study of CS-STEMI patients from a large U.S. national database (National Inpatient Sample) between 2005 and 2014. Events were then divided into four different groups: no MCS, with intra-aortic balloon pump, percutaneous ventricular assist device includes Impella or Tandem Heart or extracorporeal membrane oxygenation.
resultsBleeding complications and ALI were observed in 31,389 (18.2%) and 1,628 (0.9%) out of 172,491 admissions with CS-STEMI, respectively. Between 2005 and 2014, overall trends increased for ALI; however, the number of bleeding events decreased. ALI was associated with increased in-hospital mortality in comparison to those without any ALI. However, bleeding complications were not associated with increased in-hospital mortality. Compared to patients without complications, both bleeding and ALI were associated with increased length of stay (LOS) and hospitalization costs.
conclusionsBleeding and ALI are common complications associated with CS-STEMI in the contemporary era. Both complications are associated with increased hospital costs and LOS. These findings highlight the need to develop algorithms focused on vascular safety in CS-STEMI.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.