Evidence mapPaperPMID 32473648Full record

Observational studyCardiovascular diabetology2020

Effect of 1,5-anhydroglucitol levels on culprit plaque rupture in diabetic patients with acute coronary syndrome.

Gong Su, Ming-Xi Gao, Gen-Ling Shi, Xi-Xi Dai, Wei-Feng Yao, Tao Zhang, Shao-Wei Zhuang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Cardiovascular diabetology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gong SuDepartment of Cardiovascular Medicine, Shanghai General Hospital Baoshan Branch, No. 101 Tongtai North Road, Baoshan District, Shanghai, 200940, China. su_gong@yahoo.com.ORCID 0000-0001-6924-1636
Ming-Xi GaoDepartment of Cardiovascular Medicine, Shanghai General Hospital Baoshan Branch, No. 101 Tongtai North Road, Baoshan District, Shanghai, 200940, China.
Gen-Ling ShiDepartment of Cardiovascular Medicine, Shanghai General Hospital Baoshan Branch, No. 101 Tongtai North Road, Baoshan District, Shanghai, 200940, China.
Xi-Xi DaiDepartment of Cardiovascular Medicine, Shanghai General Hospital Baoshan Branch, No. 101 Tongtai North Road, Baoshan District, Shanghai, 200940, China.
Wei-Feng YaoDepartment of Cardiovascular Medicine, Shanghai General Hospital Baoshan Branch, No. 101 Tongtai North Road, Baoshan District, Shanghai, 200940, China.
Tao ZhangCenter of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Shao-Wei ZhuangDepartment of Cardiovascular Medicine, The Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, No. 358 Gaoqiaodatong Road, Pudong District, Shanghai, 200137, China. zhuangs66@yahoo.com.
Baogang Group (China) · CNCapital Medical University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostprandial hyperglycemia was reported to play a key role in established risk factors of coronary artery diseases (CAD) and cardiovascular events. Serum 1,5-anhydroglucitol (1,5-AG) levels are known to be a clinical marker of short-term postprandial glucose (PPG) excursions. Low serum 1,5-AG levels have been associated with occurrence of CAD. However, the relationship between 1,5-AG levels and coronary plaque rupture has not been fully elucidated. The aim of this study was to evaluate 1,5-AG as a predictor of coronary plaque rupture in diabetic patients with acute coronary syndrome (ACS).

methodsA total of 144 diabetic patients with ACS were included in this study. All patients underwent intravascular ultrasound examination, which revealed 49 patients with plaque rupture and 95 patients without plaque rupture in the culprit lesion. Fasting blood glucose (FBG), hemoglobin A

resultsPatients with ruptured plaque had significantly lower serum 1,5-AG levels, longer duration of diabetes, higher HbA

conclusionsSerum 1,5-AG may identify high risk for coronary plaque rupture in diabetic patients with ACS, which suggests PPG excursions are related to the pathogenesis of plaque rupture in diabetes.

Indexed as

Plaque, AtheroscleroticUltrasonography, InterventionalAcute Coronary SyndromeAgedBiomarkersBlood GlucoseCoronary Artery DiseaseCoronary VesselsDeoxyglucoseDiabetes Mellitus, Type 2DinoprostFemaleGlycated HemoglobinHumansMaleMiddle Aged1,5-anhydroglucitol8-epi-prostaglandin F2alphaBiomarkersBlood GlucoseDeoxyglucoseDinoprostGlycated Hemoglobinhemoglobin A1c protein, human1,5-AnhydroglucitolAcute coronary syndromeDiabetesIntravascular ultrasoundPlaque rupture

Identifiers

PMID32473648
PMCPMC7261377
OpenAlexW3032462636

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.