Evidence map›Paper›PMID 32476212›Full record

ReviewHuman brain mapping2022

ENIGMA brain injury: Framework, challenges, and opportunities.

Emily L Dennis, David Baron, Brenda Bartnik-Olson, Karen Caeyenberghs, Carrie Esopenko, Frank G Hillary, Kimbra Kenney, Inga K Koerte, Alexander P Lin, Andrew R Mayer and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Multifaceted neural and vascular pathologies after pediatric mild traumatic brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 5 countries.

Emily L DennisDepartment of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0001-7112-4009
David BaronWestern University of Health Sciences, Pomona, California, USA.
Brenda Bartnik-OlsonDepartment of Radiology, Loma Linda University Medical Center, Loma Linda, California, USA.
Karen CaeyenberghsCognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Victoria, Australia.
Carrie EsopenkoDepartment of Rehabilitation and Movement Sciences, Rutgers Biomedical Health Sciences, Newark, New Jersey, USA.
Frank G HillaryDepartment of Psychology, Pennsylvania State University, University Park, Pennsylvania, USA.
Kimbra KenneyDepartment of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Inga K KoertePsychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-1281-9286
Alexander P LinCenter for Clinical Spectroscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Andrew R MayerMind Research Network, Albuquerque, New Mexico, USA.ORCID 0000-0003-2396-5609
Stefania MondelloDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.ORCID 0000-0002-8587-3614
Alexander OlsenDepartment of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0001-8691-3860
Paul M ThompsonImaging Genetics Center, Stevens Neuroimaging & Informatics Institute, Keck School of Medicine of USC, Marina del Rey, California, USA.
David F TateDepartment of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Elisabeth A WildeDepartment of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
University of Utah · USBrigham and Women's Hospital · USDeakin University · AULoma Linda University Medical Center · USMind Research Network · USNorwegian University of Science and Technology · NOPennsylvania State University · USRutgers, The State University of New Jersey · USUniformed Services University of the Health Sciences · USUniversity of Messina · ITUniversity of Southern California · USWestern University of Health Sciences · US

Funding

Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
Sex Differences in Brain Structure and Function After Sports-Related ConcussionR01NS100952 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI KOERTE, INGA KATHARINA · 2017 to 2022
$2.9M
Longitudinal Tracking of Traumatic Brain Injury: Advanced ConnectomicsK99NS096116 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DENNIS, EMILY LARSEN · 2016 to 2017
$176k
NIBIB NIH HHS U54 EB020403NIH HHS K99NS096116NIH HHS R01NS100952NIH HHS U54EB020403NINDS NIH HHS K99 NS096116NINDS NIH HHS R01 NS100952
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a major cause of disability worldwide, but the heterogeneous nature of TBI with respect to injury severity and health comorbidities make patient outcome difficult to predict. Injury severity accounts for only some of this variance, and a wide range of preinjury, injury-related, and postinjury factors may influence outcome, such as sex, socioeconomic status, injury mechanism, and social support. Neuroimaging research in this area has generally been limited by insufficient sample sizes. Additionally, development of reliable biomarkers of mild TBI or repeated subconcussive impacts has been slow, likely due, in part, to subtle effects of injury and the aforementioned variability. The ENIGMA Consortium has established a framework for global collaboration that has resulted in the largest-ever neuroimaging studies of multiple psychiatric and neurological disorders. Here we describe the organization, recent progress, and future goals of the Brain Injury working group.

Indexed as

Brain Injuries, TraumaticNeuroimagingHumansMulticenter Studies as Topicbrain injuryconcussionENIGMAneuroimagingTBI

Identifiers

PMID32476212
PMCPMC8675432
OpenAlexW3030523186

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.