Evidence mapPaperPMID 32477270Full record

ArticleFrontiers in endocrinology2020

Pharmacotherapy for the Treatment of Overweight and Obesity in Children, Adolescents, and Young Adults in a Large Health System in the US.

Kathryn S Czepiel, Numa P Perez, Karen J Campoverde Reyes, Shreya Sabharwal, Fatima Cody Stanford

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04572217 (Medications After Adolescent Bariatric Surgery Protocol for Inadequate Weight Loss Following Sleeve Gastrectomy in Adolescents and Young Adults), which is not on this map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04572217 phase2withdrawnnot on this mapstarted 2022, after this paper: background citation

Medications After Adolescent Bariatric Surgery Protocol for Inadequate Weight Loss Following Sleeve Gastrectomy in Adolescents and Young Adults: A Pilot Feasibility Study

TypeinterventionalSponsorJaney PrattRan2022 to 2022Enrolled0ConditionsPediatric ObesityArmsTopiramate, Phentermine
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Genetics, pharmacotherapy, and dietary interventions in childhood obesity.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Biomechanical CT to Assess Bone After Sleeve Gastrectomy in Adolescents With Obesity: A Prospective Longitudinal Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kathryn S CzepielDepartment of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Numa P PerezDepartment of General Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Karen J Campoverde ReyesNeuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Shreya SabharwalDepartment of Bioethics, Harvard Medical School, Boston, MA, United States.
Fatima Cody StanfordNeuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Harvard University · USMassachusetts General Hospital · USWashington Center for Weight Management and Research · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · MASSACHUSETTS GENERAL HOSPITAL · 1994 to 2025
$6.0M
NIDDK NIH HHS L30 DK118710NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Lifestyle modifications focused on diet, physical activity, and behavior have a modest impact on weight reduction in children, adolescents, and young adults (YA) with overweight and obesity. Several anti-obesity medications (AOMs) have been approved by the Food and Drug Administration (FDA) for use among adult patients with a body mass index (BMI) ≥27 kg/m

Indexed as

Body Mass IndexWeight LossAdolescentAdultAnti-Obesity AgentsChildChild, PreschoolDietExerciseFemaleFollow-Up StudiesHumansLife StyleMaleObesityOverweightAnti-Obesity Agentsadolescentsanti-obesity medicationschildrenobesityoverweightpharmacotherapyweight loss medicationsyoung adults

Identifiers

PMID32477270
PMCPMC7237714
OpenAlexW3024464643

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.