Evidence map›Paper›PMID 32478100›Full record

ReviewFrontiers in cardiovascular medicine2020

The Evolving Understanding and Approach to Residual Cardiovascular Risk Management.

Devinder S Dhindsa, Pratik B Sandesara, Michael D Shapiro, Nathan D Wong

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06619353 (Residual CardioVascular Risk), which is not on this map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06619353 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Residual CardioVascular Risk (RCVR) After Percutaneous Coronary Intervention: A Prospective Study

Typeobservational_patient_registrySponsorCHA UniversityRan2024 to 2029Enrolled500ConditionsCoronary Artery DiseaseArmsBlood Sample, DICOM Dataset
3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 169 citations in OpenAlex.

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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Devinder S DhindsaDivision of Cardiology, Department of Medicine, Emory Clinical Cardiovascular Research Institute, Atlanta, GA, United States.
Pratik B SandesaraDivision of Cardiology, Department of Medicine, Emory Clinical Cardiovascular Research Institute, Atlanta, GA, United States.
Michael D ShapiroSection on Cardiovascular Medicine, Center for the Prevention of Cardiovascular Disease, Wake Forest Baptist Medical Center, Winston-Salem, NC, United States.
Nathan D WongHeart Disease Prevention Program, Division of Cardiology, University of California, Irvine, Irvine, CA, United States.
Emory Healthcare · USAtrium Health Wake Forest Baptist · USUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite unprecedented advances in treatment of atherosclerotic cardiovascular disease, it remains the leading cause of death and disability worldwide. Treatment of major traditional risk factors, including low-density lipoprotein-cholesterol, serves as the foundation of atherosclerotic risk reduction. However, there remains a significant residual risk of cardiovascular events despite optimal risk factor management. Beyond traditional risk factors, other drivers of residual risk have come to the forefront, including inflammatory, pro-thrombotic, and metabolic pathways that contribute to recurrent events and are often unrecognized and not addressed in clinical practice. This review will explore the evidence linking these pathways to atherosclerotic cardiovascular disease and potential future therapeutic options to attenuate residual cardiovascular risk conferred by these pathways.

Indexed as

atherosclerosiscardiovascular diseasecardiovascular risk factorsinflammationmetabolic syndromeprimary preventionresidual risksecondary prevention

Identifiers

PMID32478100
PMCPMC7237700
OpenAlexW3024277681

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.