ReviewInternational journal of molecular sciences2020
Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping?
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- The Incidence and Mortality Ratio of Ischemic Cerebrovascular Accidents in COVID-19 Cases: A Systematic Review and Meta-Analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Pooled it
- Cannabis Derivatives as Ingredients of Functional Foods to Combat the COVID-19 Pandemic.Foods (Basel, Switzerland) · 2025Review
- Association among Lifestyle and Risk Factors with SARS-CoV-2 Infection.Tuberculosis and respiratory diseases · 2023Article
- Endocannabinoid system components as potential neuroimmune therapeutic targets in tinnitus.Frontiers in neurology · 2023Article
- Neurological Involvements in COVID-19: A hospital-based study.Iranian journal of child neurology · 2023Article
- Differences in Clinical Outcomes between Smokers and Non-Smokers infected with COVID-19.Archives of Razi Institute · 2022Article
- Impact of Smoking on COVID-19 Symptoms in Non-Vaccinated Patients: A Matched Observational Study from Qatar.Journal of multidisciplinary healthcare · 2022Article
- Impact of chronic smoking on traumatic brain microvascular injury: An in vitro study.Journal of cellular and molecular medicine · 2021Article
- Review
- Assessing Vaping Views, Usage, and Vaping-Related Education Among Medical Students: A Pilot Study.Cureus · 2021Article
- Analytical methods for the identification of micro/nano metals in e-cigarette emission samples: a review.Chemicke zvesti · 2021Review
- Neuroinflammation and Its Impact on the Pathogenesis of COVID-19.Frontiers in medicine · 2021Review
- Smoking Is Correlated With the Prognosis of Coronavirus Disease 2019 (COVID-19) Patients: An Observational Study.Frontiers in physiology · 2021Article
- Smoking and COVID-19: A Scoping Review.Tobacco use insights · 2021Article
- Nanomedicine for the SARS-CoV-2: State-of-the-Art and Future Prospects.International journal of nanomedicine · 2021Review
- Understanding the Immunologic Characteristics of Neurologic Manifestations of SARS-CoV-2 and Potential Immunological Mechanisms.Molecular neurobiology · 2020Review
- The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19.The Journal of pharmacology and experimental therapeutics · 2020Review
- Why Do Some Reports Claim that the Number of COVID-19 Hospitalized Smokers is Smaller than Expected?Journal of biomedical physics & engineering · 2020Article
- Neurological Complications of SARS-CoV, MERS-CoV, and COVID-19.SN comprehensive clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The recently discovered novel coronavirus, SARS-CoV-2 (COVID-19 virus), has brought the whole world to standstill with critical challenges, affecting both health and economic sectors worldwide. Although initially, this pandemic was associated with causing severe pulmonary and respiratory disorders, recent case studies reported the association of cerebrovascular-neurological dysfunction in COVID-19 patients, which is also life-threatening. Several SARS-CoV-2 positive case studies have been reported where there are mild or no symptoms of this virus. However, a selection of patients are suffering from large artery ischemic strokes. Although the pathophysiology of the SARS-CoV-2 virus affecting the cerebrovascular system has not been elucidated yet, researchers have identified several pathogenic mechanisms, including a role for the ACE2 receptor. Therefore, it is extremely crucial to identify the risk factors related to the progression and adverse outcome of cerebrovascular-neurological dysfunction in COVID-19 patients. Since many articles have reported the effect of smoking (tobacco and cannabis) and vaping in cerebrovascular and neurological systems, and considering that smokers are more prone to viral and bacterial infection compared to non-smokers, it is high time to explore the probable correlation of smoking in COVID-19 patients. Herein, we have reviewed the possible role of smoking and vaping on cerebrovascular and neurological dysfunction in COVID-19 patients, along with potential pathogenic mechanisms associated with it.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.