Evidence map›Paper›PMID 32490812›Full record

ArticleeLife2020

Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in

Robin E Harris, Michael J Stinchfield, Sabrina L Nystrom, Daniel J McKay, Iswar K Hariharan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factors.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Hallmarks of regeneration.Cell stem cell · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Robin E HarrisArizona State University, Tempe, United States.ORCID 0000-0001-6945-6741
Michael J StinchfieldArizona State University, Tempe, United States.ORCID 0000-0002-6307-7270
Sabrina L NystromUniversity of North Carolina at Chapel Hill, Chapel Hill, United States.ORCID 0000-0003-1000-1579
Daniel J McKayUniversity of North Carolina at Chapel Hill, Chapel Hill, United States.ORCID 0000-0001-8226-0604
Iswar K HariharanUniversity of California, Berkeley, Berkeley, United States.ORCID 0000-0001-6505-0744
Arizona State University · USUniversity of North Carolina at Chapel Hill · USUniversity of California, Berkeley · US

Funding

Genetic Regulation of Developmental and Regenerative GrowthR35GM122490 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Iswar K. Hariharan · 2017 to 2026
$5.5M
Genetic and epigenetic mechanisms of developmental gene regulationR35GM128851 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Daniel J McKay · 2018 to 2026
$3.9M
American Cancer Society RP-16238-06-COUNAmerican Cancer Society RSG-17-164-01-DDCNIGMS NIH HHS R35 GM122490NIGMS NIH HHS R35 GM128851NIH HHS R35 GM122490
6 · The paper itself

Abstract

Like tissues of many organisms,

Indexed as

Enhancer Elements, GeneticGene Expression Regulation, DevelopmentalAnimalsDrosophila melanogasterDrosophila ProteinsGene SilencingImaginal DiscsRegenerationDrosophila Proteinsdevelopmental biologyD. melanogasterenhancersepigeneticregenerationregenerative medicinesilencingstem cells

Identifiers

PMID32490812
PMCPMC7299344
OpenAlexW3029532775

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.