ArticleMagnetic resonance in medicine2020
Whole-heart, ungated, free-breathing, cardiac-phase-resolved myocardial perfusion MRI by using Continuous Radial Interleaved simultaneous Multi-slice acquisitions at sPoiled steady-state (CRIMP).
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Dynamic Mode Decomposition (DMD) for Low-Latency Real-Time Cardiac MRI.Magnetic resonance in medicine · 2026Article
- Improved dynamic MRI of the wrist and heart at 0.55 T enabled by rapid 3D printed flexible coils.Nature communications · 2026Article
- Free-running time-resolved first-pass myocardial perfusion using a multi-scale dynamics decomposition: CMR-MOTUS.Magma (New York, N.Y.) · 2026Article
- Extending real-time MRI of the oral cavity using simultaneous multislice and compressed sensing.Magnetic resonance in medicine · 2026Article
- Comparison of radial versus cartesian k-space sampling in T1-weighted MRI: image quality assessment for contrast-enhanced thoracic spine transverse imaging.BMC medical imaging · 2025Article
- Improving ungated steady-state cardiac perfusion using transition bands.Magnetic resonance in medicine · 2025Article
- Free-Breathing Ungated Radial Simultaneous Multi-Slice Cardiac T1 Mapping.Journal of magnetic resonance imaging : JMRI · 2025Article
- Simultaneous multi-slice cardiac real-time MRI at 0.55T.Magnetic resonance in medicine · 2025Article
- Quantitative myocardial perfusion with a hybrid 2D simultaneous multi-slice sequence.Magnetic resonance imaging · 2023Article
- Joint CardiacBioengineering (Basel, Switzerland) · 2023Article
- Contrast-optimal simultaneous multi-slice bSSFP cine cardiac imaging at 0.55 T.Magnetic resonance in medicine · 2023Article
- Signal intensity informed multi-coil encoding operator for physics-guided deep learning reconstruction of highly accelerated myocardial perfusion CMR.Magnetic resonance in medicine · 2023Article
- Free-breathing motion-informed locally low-rank quantitative 3D myocardial perfusion imaging.Magnetic resonance in medicine · 2022Article
- Deep learning for radial SMS myocardial perfusion reconstruction using the 3D residual booster U-net.Magnetic resonance imaging · 2021Article
- Improved simultaneous multislice cardiac MRI using readout concatenated k-space SPIRiT (ROCK-SPIRiT).Magnetic resonance in medicine · 2021Article
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7 authors.
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Abstract
purposeTo develop a whole-heart, free-breathing, non-electrocardiograph (ECG)-gated, cardiac-phase-resolved myocardial perfusion MRI framework (CRIMP; Continuous Radial Interleaved simultaneous Multi-slice acquisitions at sPoiled steady-state) and test its quantification feasibility.
methodsCRIMP used interleaved radial simultaneous multi-slice (SMS) slice groups to cover the whole heart in 9 or 12 short-axis slices. The sequence continuously acquired data without magnetization preparation, ECG gating or breath-holding, and captured multiple cardiac phases. Images were reconstructed by a motion-compensated patch-based locally low-rank reconstruction. Bloch simulations were performed to study the signal-to-noise ratio/contrast-to-noise ratio (SNR/CNR) for CRIMP and to study the steady-state signal under motion. Seven patients were scanned with CRIMP at stress and rest to develop the sequence. One human and two dogs were scanned at rest with a dual-bolus method to test the quantification feasibility of CRIMP. The dual-bolus scans were performed using both CRIMP and an ungated radial SMS saturation recovery (SMS-SR) sequence with injection dose = 0.075 mmol/kg to compare the sequences in terms of SNR, cardiac phase resolution and quantitative myocardial blood flow (MBF).
resultsPerfusion images with multiple cardiac phases in all image slices with a temporal resolution of 72 ms/frame were obtained. Simulations and in-vivo acquisitions showed CRIMP kept the inner slices in steady-state regardless of motion. CRIMP outperformed SMS-SR in slice coverage (9 over 6), SNR (mean 20% improvement), and provided cardiac phase resolution. CRIMP and SMS-SR sequences provided comparable MBF values (rest systolic CRIMP = 0.58 ± 0.07, SMS-SR = 0.61 ± 0.16).
conclusionCRIMP allows for whole-heart, cardiac-phase-resolved myocardial perfusion images without ECG-gating or breath-holding. The sequence can provide MBF if an accurate arterial input function is obtained separately.
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