Evidence map›Paper›PMID 32492913›Full record

Trial reportNutrients2020

Effects of Monomeric and Oligomeric Flavanols on Kidney Function, Inflammation and Oxidative Stress in Runners: A Randomized Double-Blind Pilot Study.

Khrystyna O Semen, Antje R Weseler, Marcel J W Janssen, Marie-José Drittij-Reijnders, Jos L M L le Noble, Aalt Bast

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Changes in Novel AKI Biomarkers after Exercise. A Systematic Review.International journal of molecular sciences · 2020
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Khrystyna O SemenCampus Venlo, Faculty of Science and Engineering, Maastricht University, 5911 BV Venlo, The Netherlands.ORCID 0000-0002-2209-3653
Antje R WeselerDepartment of Pharmacology and Toxicology, Faculty of Health, Medicine, and Life Sciences, Maastricht University, 6200 MD Maastricht, The Netherlands.
Marcel J W JanssenDepartment of Clinical Chemistry and Haematology, VieCuri Medical Center Noord Limburg, 5912 BL Venlo, The Netherlands.
Marie-José Drittij-ReijndersDepartment of Pharmacology and Toxicology, Faculty of Health, Medicine, and Life Sciences, Maastricht University, 6200 MD Maastricht, The Netherlands.
Jos L M L le NobleDepartment of Pharmacology and Toxicology, Faculty of Health, Medicine, and Life Sciences, Maastricht University, 6200 MD Maastricht, The Netherlands.
Aalt BastCampus Venlo, Faculty of Science and Engineering, Maastricht University, 5911 BV Venlo, The Netherlands.ORCID 0000-0002-5383-2789
Maastricht University · NLVieCuri Medisch Centrum · NL

Funding

Universiteit Maastricht INC002
6 · The paper itself

Abstract

Nonsteroidal anti-inflammatory drugs are frequently used by athletes in order to prevent musculoskeletal pain and improve performance. In combination with strenuous exercise, they can contribute to a reduction of renal blood flow and promote development of kidney damage. We aimed to investigate whether monomeric and oligomeric flavanols (MOF) could reduce the severity of kidney injuries associated with the intake of 400-mg ibuprofen followed by the completion of a half-marathon in recreational athletes. In this double-blind, randomized study, the original MOF blend of extracts from grape seeds (

Indexed as

AntioxidantsAthletesAthletic PerformanceDietary SupplementsFlavonoidsInflammationKidney DiseasesMusculoskeletal PainOxidative StressPhytotherapyPlant ExtractsRunningDouble-Blind MethodHumansKidneyPilot ProjectsAntioxidantsFlavonoidsPlant Extractsexerciseflavanolsibuprofeninflammationkidney functionneutrophil gelatinase-associated lipocalin

Identifiers

PMID32492913
PMCPMC7353060
OpenAlexW3029575560

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.