Evidence map›Paper›PMID 32496897›Full record

ReviewRNA biology2020

The diversity, plasticity, and adaptability of cap-dependent translation initiation and the associated machinery.

Katherine L B Borden, Laurent Volpon

Open access · hybridAbstract readReview
In one paragraph

Review in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Med9 Is a Novel eIF4E-Interacting Protein inInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. From Structure to Function of Promoters and 5'UTRs in Maize.International journal of molecular sciences · 2026
    Review
  5. Review
  6. eIF4E assembly intobioRxiv : the preprint server for biology · 2025
    Article
  7. Evolutionarily conserved grammar rules viral factories of amoeba-infecting members of the hyperdiverseProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Dynamics and Regulation of mRNA Cap Recognition by Human eIF4F.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Stress response regulation of mRNA translation: Implications for antioxidant enzyme expression in cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Review
  14. Review
  15. Review
  16. Article
  17. The mCancers · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Katherine L B BordenInstitute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal , Montreal, Québec, Canada.ORCID 0000-0003-2188-5074
Laurent VolponInstitute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal , Montreal, Québec, Canada.
Institute for Research in Immunology and Cancer · CA

Funding

CIHR PJT159785
6 · The paper itself

Abstract

Translation initiation is a critical facet of gene expression with important impacts that underlie cellular responses to stresses and environmental cues. Its dysregulation in many diseases position this process as an important area for the development of new therapeutics. The gateway translation factor eIF4E is typically considered responsible for 'global' or 'canonical' m

Indexed as

Gene Expression RegulationProtein BiosynthesisRNA CapsAnimalsDisease SusceptibilityEukaryotic Initiation Factor-4EHumansMethylationModels, BiologicalModels, MolecularMolecular ConformationPeptide Chain Initiation, TranslationalProtein Processing, Post-TranslationalRNA-Binding ProteinsRNA, MessengerStress, PhysiologicalEukaryotic Initiation Factor-4ERNA-Binding ProteinsRNA CapsRNA, MessengerTranscription FactorscancereIF4ERNA processingRNA regulonstherapeuticsTranslation

Identifiers

PMID32496897
PMCPMC7549709
OpenAlexW3033532300

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.