Evidence map›Paper›PMID 32503254›Full record

ArticleMolecules (Basel, Switzerland)2020

Extra Virgin Olive Oil Phenols Dilate the Rat Mesenteric Artery by Activation of BK

Rossana D'Agostino, Laura Barberio, MariaCarmela Gatto, Innocenzo Muzzalupo, Maurizio Mandalà

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Natural Products to Promote Vascular Health.Handbook of experimental pharmacology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rossana D'AgostinoDepartment of Biology, Ecology & Earth Sciences, University of Calabria, 87036 Rende (CS), Italy.
Laura BarberioDepartment of Biology, Ecology & Earth Sciences, University of Calabria, 87036 Rende (CS), Italy.
MariaCarmela GattoDepartment of Biology, Ecology & Earth Sciences, University of Calabria, 87036 Rende (CS), Italy.
Innocenzo MuzzalupoResearch Centre for Olive, Citrus and Tree Fruit-Council for Agricultural Research and Economics, 87036 Rende (CS), Italy.ORCID 0000-0002-0264-1392
Maurizio MandalàDepartment of Biology, Ecology & Earth Sciences, University of Calabria, 87036 Rende (CS), Italy.ORCID 0000-0003-3736-0205
University of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence has shown the beneficial health effects of extra virgin olive oil (EVOO) consumption in reducing blood pressure and preventing the risk of developing hypertension. Some studies associate the hypotensive activity of EVOO to a minor component-the phenols. This study was designed to investigate the effects of EVOO phenols on the rat resistance mesenteric artery (MA) and to find out the possible vascular pathways involved. The experiments were carried out using a pressurized myograph, which allowed the effects of phenols on isolated MA to be tested under different conditions: (a) with endothelium removed; (b) with inhibition of nitric oxide synthase by N

Indexed as

AnimalsCalciumLarge-Conductance Calcium-Activated Potassium ChannelsMaleMesenteric ArteriesMuscle, Smooth, VascularOlive OilPhenolsRatsRats, Sprague-DawleyVasodilationVasodilator AgentsCalciumLarge-Conductance Calcium-Activated Potassium ChannelsOlive OilPhenolsVasodilator AgentsBKCa2+ channelsextra virgin olive oil phenolsmesenteric arterysmooth muscle cellsvasodilation

Identifiers

PMID32503254
PMCPMC7321220
OpenAlexW3033512664

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.