ArticleJournal of family medicine and primary care2020
Metabolic changes in the patients on second-line highly active antiretroviral therapy (HAART): A prospective cohort study from north India.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- A systematic review assessing body mass index and waist circumference as predictors for the development of type 2 diabetes mellitus among people living with HIV on antiretroviral therapy.BMC infectious diseases · 2025Pooled it
- The Impact of Selected Regimens of Chronic HIV-Antiretroviral Treatment on Glycemic Control Markers and Correlates: A Systematic Review and Meta-Analysis Protocol.Health science reports · 2025Review
- Metabolic syndrome among people living with HIV in Ethiopia: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2023Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn India, there is a genetic predisposition to insulin resistance and cardiovascular risk, the impact of ART (antiretroviral therapy) on lipid profile and blood sugar may be significant. The study of potential implications of highly active antiretroviral therapy (HAART)-associated metabolic syndrome is critical to prevent cardiovascular diseases in the Indian population.
aimsThis study was done to determine the prevalence of metabolic changes (dyslipidaemia, hyperglycemia and insulin resistance) among HIV patients on second-line ART. SETTINGS AND
designA prospective cohort study. METHODS AND MATERIALS: We enrolled 150 patients, who were started on second-line HAART. Patients were investigated for fasting blood sugar, lipid profile and insulin level at baseline and after 6 months. STATISTICAL ANALYSIS: The data were analysed using SPSS software (version 20; IBM Corp., Armonk, N.Y., USA). Student's
resultsThere was a significant increase in serum cholesterol, LDL and triglyceride in patients with protease inhibitors (PIs) containing regimens. LDL levels were increased from 65 to 80 mg/dL (
conclusionsAppropriate drug selection with timely switching of ART is crucial to prevent metabolic complications in patients taking long-term PIs.
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