Evidence map›Paper›PMID 32512939›Full record

ArticleCells2020

Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation.

Gema Frühbeck, Inmaculada Balaguer, Leire Méndez-Giménez, Víctor Valentí, Sara Becerril, Victoria Catalán, Javier Gómez-Ambrosi, Camilo Silva, Javier Salvador, Giuseppe Calamita and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

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  17. Aquaporins in Cancer Biology.Frontiers in oncology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Gema FrühbeckMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8305-7154
Inmaculada BalaguerMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Leire Méndez-GiménezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Víctor ValentíCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Sara BecerrilMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Victoria CatalánMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Javier Gómez-AmbrosiMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5601-1604
Camilo SilvaCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Javier SalvadorCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Giuseppe CalamitaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", 70125 Bari, Italy.ORCID 0000-0003-4666-9546
María M MalagónCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Amaia RodríguezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-2180-461X
Instituto de Salud Carlos III · ESClinica Universidad de Navarra · ESHospital General Universitario Gregorio Marañón · ESUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporin-11 (AQP11) is expressed in human adipocytes, but its functional role remains unknown. Since AQP11 is an endoplasmic reticulum (ER)-resident protein that transports water, glycerol, and hydrogen peroxide (H

Indexed as

AdipocytesAdultAquaporinsCell DifferentiationDiabetes Mellitus, Type 2Endoplasmic Reticulum StressFemaleGene SilencingHumansInflammationIntra-Abdominal FatLipolysisMaleMiddle AgedModels, BiologicalObesityAQP11 protein, humanAquaporinsTransforming Growth Factor beta1Tumor Necrosis Factor-alphaaquaporinsendoplasmic reticulum stressobesity

Identifiers

PMID32512939
PMCPMC7349025
OpenAlexW3033942084

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.