Evidence map›Paper›PMID 32517352›Full record

ArticleCells2020

Phosphoinositide Profile of the Mouse Retina.

Stella Finkelstein, Sidney M Gospe, Kai Schuhmann, Andrej Shevchenko, Vadim Y Arshavsky, Ekaterina S Lobanova

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  3. Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Functional compartmentalization of photoreceptor neurons.Pflugers Archiv : European journal of physiology · 2021
    Review
  14. Compartmentalization of Photoreceptor Sensory Cilia.Frontiers in cell and developmental biology · 2021
    Review
  15. The Enigmatic Role of Lipids in Cilia Signaling.Frontiers in cell and developmental biology · 2020
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Stella FinkelsteinDepartment of Ophthalmology, Duke University, Durham, NC 27710, USA.
Sidney M GospeDepartment of Ophthalmology, Duke University, Durham, NC 27710, USA.ORCID 0000-0003-2838-7983
Kai SchuhmannMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Andrej ShevchenkoMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Vadim Y ArshavskyDepartment of Ophthalmology, Duke University, Durham, NC 27710, USA.ORCID 0000-0001-8394-3650
Ekaterina S LobanovaDepartment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-8309-7199
Duke University · USMax Planck Institute of Molecular Cell Biology and Genetics · DEUniversity of Florida · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Goldis Malek · 1985 to 2026
$19.3M
Molecular mechanisms of photoreceptor outer segment morphogenesisR01EY012859 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI ARSHAVSKY, VADIM Y · 2000 to 2022
$10.0M
Transducin movement and photoreceptor light adaptationR01EY010336 · NEI · UNIVERSITY OF WISCONSIN MADISON · PI ARSHAVSKY, VADIM Y · 1994 to 2012
$6.3M
Transcriptional Control of Proteostsis in PhotoreceptorsR01EY030043 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOBANOVA, EKATERINA · 2019 to 2023
$1.8M
NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY010336NEI NIH HHS R01 EY012859NEI NIH HHS R01 EY030043
6 · The paper itself

Abstract

Phosphoinositides are known to play multiple roles in eukaryotic cells. Although dysregulation of phosphoinositide metabolism in the retina has been reported to cause visual dysfunction in animal models and human patients, our understanding of the phosphoinositide composition of the retina is limited. Here, we report a characterization of the phosphoinositide profile of the mouse retina and an analysis of the subcellular localization of major phosphorylated phosphoinositide forms in light-sensitive photoreceptor neurons. Using chromatography of deacylated phosphatidylinositol headgroups, we established PI(4,5)P

Indexed as

AnimalsFatty AcidsLipidomicsMice, Inbred C57BLPhosphatidylinositolsPhosphorylationRetinaRetinal Rod Photoreceptor CellsSubcellular FractionsFatty AcidsPhosphatidylinositolsphosphatidylinositol bisphosphatephosphatidylinositol phosphatephotoreceptorretina

Identifiers

PMID32517352
PMCPMC7349851
OpenAlexW3033149024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.