Evidence map›Paper›PMID 32528735›Full record

ArticleImmunometabolism2020

Multiple Sclerosis: Lipids, Lymphocytes, and Vitamin D.

Colleen E Hayes, James M Ntambi

Open access · diamondAbstract read
In one paragraph

Article in Immunometabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Dysregulation of Monounsaturated Fatty Acids is Related to α-Synuclein in Multiple System Atrophy.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Impact of different milling techniques towards vitamin DJournal of food science and technology · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Fatty Acid Synthesis in Glial Cells of the CNS.International journal of molecular sciences · 2021
    Review
  18. Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease.International journal of molecular sciences · 2020
    Article
  19. Review
  20. Epstein-Barr Virus and Multiple Sclerosis.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Colleen E HayesDepartment of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
James M NtambiDepartment of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.
University of Wisconsin–Madison · US

Funding

Role of Stearoyl-CoA Desaturase in MetabolismR01DK062388 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI NTAMBI, JAMES M. · 2002 to 2010
$2.6M
Role of Liver Stearoyl-CoA Desaturase-1 in the Regulation of MetabolismR01DK118093 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI NTAMBI, JAMES M. · 2018 to 2020
$1.1M
NIDDK NIH HHS R01 DK062388NIDDK NIH HHS R01 DK118093
6 · The paper itself

Abstract

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. We review the two core MS features, myelin instability, fragmentation, and remyelination failure, and dominance of pathogenic CD4

Indexed as

epigenetic regulationmethionine cyclemultiple sclerosismyelinnervonic acidobesityoligodendrocytesT lymphocytesvitamin D

Identifiers

PMID32528735
PMCPMC7289029
OpenAlexW3021116203

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.