Evidence mapPaperPMID 32529113Full record

ArticleArchives of medical sciences. Atherosclerotic diseases2020

Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio are associated with cryptogenic stroke in patients with patent foramen ovale.

Fatma Nihan Turhan Caglar, Murat Erdem Alp, Nilay Karabulut, Nilgun Isiksacan, Fahrettin Katkat, Hulya Cebe, Ersan Oflar, Didem Melis Oztas, Orhan Rodoplu, Orcun Unal and 3 more

Abstract read
In one paragraph

Article in Archives of medical sciences. Atherosclerotic diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fatma Nihan Turhan CaglarCardiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Murat Erdem AlpCardiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Nilay KarabulutCardiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Nilgun IsiksacanBiochemistry Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Fahrettin KatkatCardiology Department, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Hulya CebeCardiology Department, Ercis State Hospital, Van, Turkey.
Ersan OflarCardiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Didem Melis OztasCardiovascular Surgery Clinic, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Orhan RodopluCardiovascular Surgery Clinic, Kadikoy Medicana Hospital, Istanbul, Turkey.
Orcun UnalCardiovascular Surgery Clinic, Yedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey.
Cenk ConkbayirDepartment of Cardiology, Near East University, Nicosia, Cyprus.
Faruk AkturkCardiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Murat UgurlucanDepartment of Cardiovascular Surgery, Medical Faculty, Istanbul Medipol University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough most ischaemic strokes are due to cardioembolism, about 25-40% of strokes are cryptogenic. Patent foramen ovale has been associated with cryptogenic stroke; however, the precise mechanism of this association has not been demonstrated. The aim of this study was to evaluate the association between inflammatory markers and cryptogenic stroke in patients with patent foramen ovale. MATERIAL AND

methodsWe included 206 patients with patent foramen ovale. Ninety-four (45.63%) out of 206 patients had had stroke, and 112 (54.37%) had not had stroke. The ratio of the total neutrophil count to the total lymphocyte count was defined as the neutrophil to lymphocyte ratio, and the ratio of the absolute platelet count to the absolute lymphocyte count was determined as the platelet to lymphocyte count.

resultsThe neutrophil to lymphocyte ratio was significantly higher in patients who had stroke than in those who did not (2.41 ±1.69 vs. 2.19 ±1.74,

conclusionsThis study demonstrated that elevated neutrophil to lymphocyte ratio and platelet to lymphocyte count could be associated with cryptogenic stroke in patients with patent foramen ovale.

Indexed as

neutrophil/lymphocyte ratiopatent foramen ovaleplatelet/lymphocyte ratiostroke

Identifiers

PMID32529113
PMCPMC7277521

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.