Evidence map›Paper›PMID 32531941›Full record

ArticleNutrients2020

Poor Adherence to Mediterranean Diet and Serum Lipopolysaccharide are Associated with Oxidative Stress in Patients with Non-Alcoholic Fatty Liver Disease.

Francesco Baratta, Daniele Pastori, Simona Bartimoccia, Vittoria Cammisotto, Nicholas Cocomello, Alessandra Colantoni, Cristina Nocella, Roberto Carnevale, Domenico Ferro, Francesco Angelico and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Francesco BarattaI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Daniele PastoriI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Simona BartimocciaI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Vittoria CammisottoI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Nicholas CocomelloI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Alessandra ColantoniI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Cristina NocellaI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Roberto CarnevaleDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina 04015, Italy.
Domenico FerroI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Francesco AngelicoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
Francesco VioliI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Maria Del BenI Clinica Medica, Department of Clinical Internal, Anestesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome 00185, Italy.
Sapienza University of Rome · ITClinica Mediterranea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress plays a pivotal role in non-alcoholic fatty liver disease (NAFLD). Factors inducing oxidative stress in NAFLD may be several; however, a relationship with the adherence to Mediterranean Diet (Med-diet) and with serum lipopolysaccharide (LPS) has been poorly investigated in this setting. The aim was to investigate factors associated with impaired oxidative stress in NAFLD, focusing on the potential role of LPS and Med-diet. We enrolled 238 consecutive outpatients from the PLINIO study, in whom we measured the soluble Nox2-derived peptide (sNox2-dp), a marker of systemic oxidative stress, and serum LPS. Adherence to Med-diet was investigated by a nine-item validated dietary questionnaire. Serum sNox2-dp and LPS were higher in patients with NAFLD compared to those without (25.0 vs. 9.0 pg/mL,

Indexed as

Diet, MediterraneanOxidative StressAdultAgedAnimalsBiomarkersFemaleFishesHumansLipopolysaccharidesMaleMiddle AgedNADPH Oxidase 2Non-alcoholic Fatty Liver DiseaseNutritional Physiological PhenomenaWineBiomarkersLipopolysaccharidesNADPH Oxidase 2lipopolysaccharideMediterranean dietNon-alcoholic fatty liver diseaseNox2-derived peptideoxidative stress

Identifiers

PMID32531941
PMCPMC7352324
OpenAlexW3035448663

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.