Evidence map›Paper›PMID 32537470›Full record

ArticleJournal of immunology research2020

The Impact of Psoriasis and Metabolic Syndrome on the Systemic Inflammation and Oxidative Damage to Nucleic Acids.

Drahomira Holmannova, Lenka Borska, Ctirad Andrys, Pavel Borsky, Jan Kremlacek, Kvetoslava Hamakova, Vit Rehacek, Andrea Malkova, Tereza Svadlakova, Vladimir Palicka and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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  5. FermentedInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Drahomira HolmannovaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0002-9865-9991
Lenka BorskaInstitute of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0002-8580-1485
Ctirad AndrysInstitute of Clinical Immunology and Allergology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-6489-8786
Pavel BorskyInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-5253-2808
Jan KremlacekInstitute of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-8641-4287
Kvetoslava HamakovaClinic of Dermatology and Venereology, University Hospital Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0003-4736-463X
Vit RehacekTransfusion Center, University Hospital, Hradec Kralove 500 03, Czech Republic.
Andrea MalkovaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-9444-8065
Tereza SvadlakovaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0002-1581-5531
Vladimir PalickaInstitute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-7236-1647
Jan KrejsekInstitute of Clinical Immunology and Allergology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0003-2778-6800
Zdenek FialaInstitute of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Czech Republic.ORCID https://orcid.org/0000-0001-9978-5757
Charles University · CZUniversity Hospital Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsoriasis is a chronic systemic inflammatory disease associated with a wide range of comorbidities, including metabolic syndrome (MetS). Serum calprotectin, ANGPTL8, and oxidative damage to nucleic acids might be associated with both diseases. The presented study describes the influence of psoriasis and MetS on the serum levels of markers of systemic inflammation (calprotectin and ANGPTL8) and markers of oxidative damage to nucleic acids. The applicability of serum levels of calprotectin and ANGPTL8 for monitoring of the activity of psoriasis (diagnostic markers) is also evaluated.

methodsClinical examination (PASI score, MetS), enzyme-linked immunosorbent assay (ELISA), and Enzyme Immunoassay (EIA). Serum calprotectin, ANGPTL8, 8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanosine, and 8-hydroxyguanine.

Indexed as

AdolescentAdultAgedAged, 80 and overAngiopoietin-Like Protein 8Angiopoietin-like ProteinsBiomarkersDNA DamageFemaleHumansInflammationLeukocyte L1 Antigen ComplexMaleMetabolic SyndromeMiddle AgedNucleic AcidsAngiopoietin-Like Protein 8Angiopoietin-like ProteinsANGPTL8 protein, humanBiomarkersLeukocyte L1 Antigen ComplexNucleic AcidsPeptide Hormones

Identifiers

PMID32537470
PMCPMC7256681
OpenAlexW3027937462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.