Evidence map›Paper›PMID 32537682›Full record

SynthesisDrugs & aging2020

Attitudes Towards Deprescribing Among Older Adults with Limited Life Expectancy and Their Relatives: A Systematic Review.

Alaa Burghle, Carina Lundby, Jesper Ryg, Jens Søndergaard, Anton Pottegård, Dorthe Nielsen, Trine Graabæk

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Drugs & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Medication Use Quality and Safety in Older Adults: 2019 Update.Journal of the American Geriatrics Society · 2021
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alaa BurghleHospital Pharmacy Funen, Odense University Hospital, Solfaldsvej 38, Entrance 208, 5000, Odense C, Denmark. alaa.hassan.burghle@rsyd.dk.ORCID http://orcid.org/0000-0002-3759-7993
Carina LundbyHospital Pharmacy Funen, Odense University Hospital, Solfaldsvej 38, Entrance 208, 5000, Odense C, Denmark.ORCID http://orcid.org/0000-0002-2121-6252
Jesper RygDepartment of Geriatric Medicine, Odense University Hospital, Odense C, Denmark.ORCID http://orcid.org/0000-0002-8641-3062
Jens SøndergaardResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense C, Denmark.ORCID http://orcid.org/0000-0002-1629-1864
Anton PottegårdHospital Pharmacy Funen, Odense University Hospital, Solfaldsvej 38, Entrance 208, 5000, Odense C, Denmark.ORCID http://orcid.org/0000-0001-9314-5679
Dorthe NielsenMigrant Health Clinic, Odense University Hospital, Odense C, Denmark.ORCID http://orcid.org/0000-0002-3954-7551
Trine GraabækClinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense C, Denmark.ORCID http://orcid.org/0000-0001-6848-3107

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeprescribing is of particular importance in older adults with limited life expectancy since this population group is highly susceptible to the potential harms of inappropriate medications.

objectiveThis systematic review aimed to explore attitudes towards deprescribing among older adults with limited life expectancy and their relatives.

methodsA systematic literature review was conducted in the MEDLINE and EMBASE databases from inception to October 2019. Inclusion criteria were studies specifically describing attitudes towards deprescribing among older adults (≥ 65 years) with limited life expectancy and/or their relatives regardless of study type. Results were analyzed, inspired by the Joanna Briggs Institute's method for synthesis of qualitative data.

resultsA total of 842 studies were identified and screened; 84 were full-text assessed for eligibility and 7 were ultimately included. Two studies investigated the attitudes of older adults with limited life expectancy and their relatives towards deprescribing of statins and donepezil, respectively, while the five remaining studies related to attitudes towards deprescribing in general. Four main themes were identified: (1) the well-being of older adults with limited life expectancy; (2) involvement of older adults and their relatives in deprescribing; (3) the role of health care professionals in deprescribing; and (4) medication-related factors affecting deprescribing. Within each of these themes, several subthemes were identified.

conclusionsAttitudes towards deprescribing among older adults with limited life expectancy and their relatives vary and highlight several barriers and enablers to the deprescribing process. Several of these factors must be addressed to successfully implement deprescribing initiatives in this patient group.

Indexed as

DeprescriptionsHealth Knowledge, Attitudes, PracticeAgedDonepezilFamilyHealth PersonnelHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLife ExpectancyProfessional RoleDonepezilHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID32537682

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.