Evidence map›Paper›PMID 32539474›Full record

ArticleAIDS care2020

Relationship between economic insecurity, inflammation, monocyte activation and intestinal integrity in children living with HIV in Uganda.

Sahera Dirajlal-Fargo, Zainab Albar, Abdus Sattar, Manjusha Kulkarni, Emily Bowman, Nicholas Funderburg, Rashidah Nazzinda, Cissy Kityo, Victor Musiime, Grace A McComsey

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sahera Dirajlal-FargoUniversity Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Zainab AlbarCase Western Reserve University, Cleveland, OH, USA.
Abdus SattarCase Western Reserve University, Cleveland, OH, USA.
Manjusha KulkarniOhio State University School of Health and Rehabilitation Sciences, Columbus, OH, USA.
Emily BowmanOhio State University School of Health and Rehabilitation Sciences, Columbus, OH, USA.
Nicholas FunderburgOhio State University School of Health and Rehabilitation Sciences, Columbus, OH, USA.
Rashidah NazzindaJoint Clinical Research Centre, Kampala, Uganda.
Cissy KityoJoint Clinical Research Centre, Kampala, Uganda.
Victor MusiimeJoint Clinical Research Centre, Kampala, Uganda.
Grace A McComseyUniversity Hospitals Cleveland Medical Center, Cleveland, OH, USA.ORCID 0000-0003-2690-8888
Joint Clinical Research Centre · UGThe Ohio State University · USCase Western Reserve University · USUniversity Hospitals of Cleveland · US

Funding

Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Cardiovascular disease and inflammation in Ugandan children with HIVK23HD088295 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI DIRAJLAL-FARGO, SAHERA · 2016 to 2020
$799k
NCATS NIH HHS UM1 TR004528NICHD NIH HHS K23 HD088295
6 · The paper itself

Abstract

We aimed to evaluate differences in socio-economic variables in a Ugandan cohort of children with perinatally acquired HIV (PHIVs), HIV exposed uninfected (HEU) and HIV unexposed uninfected (HIV-) children and their associations with markers of inflammation and intestinal integrity. This is a cross-sectional study in 57 PHIV, 59 HEU and 56 HIV - children aged 2-10 years old enrolled in Uganda. Mean age of all participants was 7 years and 55% were girls. Compared to HEU and HIV - children, PHIVs were more likely to have parents that only completed a primary education, live in a household without electricity and live in poverty (

Indexed as

Gastrointestinal MicrobiomeHIV InfectionsMonocytesCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesFemaleHumansInflammationMalePregnancyPregnancy Complications, InfectiousPrenatal Exposure Delayed EffectsSocioeconomic FactorsUgandaeconomic vulnerabilityHIV exposed uninfectedimmune activationinflammationintestinal integrityPediatric HIVUganda

Identifiers

PMID32539474
PMCPMC9346953
OpenAlexW3035036658

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.