Evidence map›Paper›PMID 32542223›Full record

ReviewMayo Clinic proceedings. Innovations, quality & outcomes2020

Hormonal Contribution to Liver Regeneration.

Anan A Abu Rmilah, Wei Zhou, Scott L Nyberg

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Mayo Clinic proceedings. Innovations, quality & outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure.Journal of clinical and translational hepatology · 2026
    Review
  2. Signal control during tissue regeneration in adult animals.Nature reviews. Molecular cell biology · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mitochondria-derived HCell death & disease · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. MAPK/ERK Pathway as a Central Regulator in Vertebrate Organ Regeneration.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anan A Abu RmilahDivision of Transplantation Surgery, Mayo Clinic, Rochester, MN.
Wei ZhouDivision of Transplantation Surgery, Mayo Clinic, Rochester, MN.
Scott L NybergDivision of Transplantation Surgery, Mayo Clinic, Rochester, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An understanding of the molecular basis of liver regeneration will open new horizons for the development of novel therapies for chronic liver failure. Such therapies would solve the drawbacks associated with liver transplant, including the shortage of donor organs, long waitlist time, high medical costs, and lifelong use of immunosuppressive agents. Regeneration after partial hepatectomy has been studied in animal models, particularly fumarylacetoacetate hydrolase-deficient (

Indexed as

CDK, cyclin-dependent kinaseEGF, epidermal growth factorEGFR, EGF receptorERK, extracellular signal-regulated kinaseFAH, fumarylacetoacetate hydrolaseGH, growth hormoneGhr-/-, growth hormone receptor gene knockouthESC, human embryonic stem cellHGF, hepatocyte growth factorhiPSC, human induced pluripotent stem cellsHNF, hepatocyte nuclear factorHPC, hepatic progenitor cellIGF, insulinlike growth factorIL, interleukinInsP3, inositol 1,4,5-trisphosphateIR, insulin receptorJNK, JUN N-terminal kinaseLDLT, living donor liver transplantLRP, low-density lipoprotein-related proteinMAPK, mitogen-activated protein kinasemRNA, messenger RNAmTOR, mammalian target of rapamycinNF-κβ, nuclear factor κβNOS, nitric oxide synthaseNTBC, 2-nitro-4-trifluoro-methyl-benzoyl-1,3-cyclohexanedionePCNA, proliferating cell nuclear antigenPCR, polymerase chain reactionPH, partial hepatectomyPI3K, phosphatidylinositol-4,5-bisphosphate 3-kinasePKB, protein kinase BPTU, 6-n-propyl-2-thiouracilROS, reactive oxygen speciesSTAT, signal transducer and activator of transcriptionT3, triiodothyronineTGF, transforming growth factorTNF, tumor necrosis factorTR, thyroid receptor

Identifiers

PMID32542223
PMCPMC7283948

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.