Evidence map›Paper›PMID 32545834›Full record

ArticleBiomedicines2020

Leucine Potentiates Glucose-mediated

Brenda Huska, Sarah Niccoli, Christopher P Phenix, Simon J Lees

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brenda HuskaBiology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Sarah NiccoliMedical Sciences, Lakehead University Faculty of Medicine, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0001-5832-1980
Christopher P PhenixNorthern Ontario School of Medicine, Medical Sciences Division, Thunder Bay, ON P7B 5E1, Canada.ORCID 0000-0001-8392-5268
Simon J LeesBiology, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Lakehead University · CAUniversity of Saskatchewan · CA

Funding

Natural Sciences and Engineering Research Council of Canada 2016-06593Northern Ontario School of Medicine Research Support Fund awarded 2014
6 · The paper itself

Abstract

Significant depots of brown adipose tissue (BAT) have been identified in many adult humans through positron emission tomography (PET), with the amount of BAT being inversely correlated with obesity. As dietary activation of BAT has implications for whole body glucose metabolism, leucine was used in the present study to determine its ability to promote BAT activation resulting in increased glucose uptake. In order to assess this, 2-deoxy-2-(fluorine-18)fluoro-d-glucose (

Indexed as

diet-induced thermogenesisglucose metabolisminterscapular brown adipose tissuenon-shivering thermogenesisobesitypositron emission tomographypropranololUCP-1

Identifiers

PMID32545834
PMCPMC7345234
OpenAlexW3035740050

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.