Evidence map›Paper›PMID 32546559›Full record

ArticleBMJ supportive & palliative care2020

Anticipatory prescribing in community end-of-life care in the UK and Ireland during the COVID-19 pandemic: online survey.

Bárbara Antunes, Ben Bowers, Isaac Winterburn, Michael P Kelly, Robert Brodrick, Kristian Pollock, Megha Majumder, Anna Spathis, Iain Lawrie, Rob George and 2 more

Abstract read
In one paragraph

Article in BMJ supportive & palliative care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Learning from end-of-life injectable medication patient safety incidents in the community: a mixed-methods analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  3. Article
  4. Challenges to timely access to out-of-hours end-of-life medications: a qualitative study in UK primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Anticipatory syringe pumps: benefits and risks.BMJ supportive & palliative care · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bárbara AntunesDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK bc521@medschl.cam.ac.uk.ORCID http://orcid.org/0000-0003-1655-7391
Ben BowersDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.ORCID http://orcid.org/0000-0001-6772-2620
Isaac WinterburnDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.
Michael P KellyDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.
Robert BrodrickCommunity Specialist Palliative Care Team, Arthur Rank Hospice Charity, Cambridge, UK.
Kristian PollockSchool of Nursing, University of Nottingham, Nottingham, Nottinghamshire, UK.
Megha MajumderDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.
Anna SpathisDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.
Iain LawriePalliative Medicine, North Manchester General Hospital, Manchester, UK.
Rob GeorgeMedicine, St Christopher's Hospice, London, UK.
Richella RyanDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.
Stephen BarclayDepartment of Public Health and Primary Care, University of Cambridge Primary Care Unit, Cambridge, Cambridgeshire, UK.ORCID http://orcid.org/0000-0002-4505-7743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnticipatory prescribing (AP) of injectable medications in advance of clinical need is established practice in community end-of-life care. Changes to prescribing guidelines and practice have been reported during the COVID-19 pandemic. AIMS AND

objectivesTo investigate UK and Ireland clinicians' experiences concerning changes in AP during the COVID-19 pandemic and their recommendations for change.

methodsOnline survey of participants at previous AP national workshops, members of the Association for Palliative Medicine of Great Britain and Ireland and other professional organisations, with snowball sampling.

resultsTwo hundred and sixty-one replies were received between 9 and 19 April 2020 from clinicians in community, hospice and hospital settings across all areas of the UK and Ireland. Changes to AP local guidance and practice were reported: route of administration (47%), drugs prescribed (38%), total quantities prescribed (35%), doses and ranges (29%). Concerns over shortages of nurses and doctors to administer subcutaneous injections led 37% to consider drug administration by family or social caregivers, often by buccal, sublingual and transdermal routes. Clinical contact and patient assessment were more often remote via telephone or video (63%). Recommendations for regulatory changes to permit drug repurposing and easier community access were made.

conclusionsThe challenges of the COVID-19 pandemic for UK community palliative care has stimulated rapid innovation in AP. The extent to which these are implemented and their clinical efficacy need further examination.

Indexed as

CaregiversDrug Administration RoutesAdministration, BuccalAdministration, SublingualAnalgesics, Non-NarcoticAnalgesics, OpioidBetacoronavirusCoronavirus InfectionsCOVID-19FentanylGeneral PractitionersHospice CareHospicesHumansHypnotics and SedativesIrelandAnalgesics, Non-NarcoticAnalgesics, OpioidFentanylHypnotics and SedativesLorazepamMethotrimeprazineMuscarinic Antagonistsdrug administrationend of life carehome carenursing home caresupportive careterminal care

Identifiers

PMID32546559
PMCPMC7335692

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.