Evidence map›Paper›PMID 32547080›Full record

ArticleOncoTargets and therapy2020

MiR-181c-5p Mitigates Tumorigenesis in Cervical Squamous Cell Carcinoma via Targeting Glycogen Synthase Kinase 3β Interaction Protein (GSKIP).

Niuniu Li, Chun Cheng, Tieyan Wang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in OncoTargets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Down-Regulation ofFrontiers in oncology · 2020
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Niuniu Li *Department of Gynecology and Obstetrics of Shiyan, Taihe Hospital of Hubei Province, Shiyan, Hubei 442000, People's Republic of China.
Chun Cheng *Department of Pediatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Edong Healthcare Group, Huangshi, Hubei 435000, People's Republic of China.
Tieyan WangClinical Pathology Department of Shiyan, Taihe Hospital of Hubei Province, Shiyan, Hubei 442000, People's Republic of China.
Taihe Hospital · CNHubei Polytechnic University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cancer (CC) is a highly prevalent cancer and one of the main causes of death among women worldwide. The miR-181 family has turned out to be associated with tumorigenesis in a variety of tumors by regulating the expression of tumor-related genes. However, the mechanisms and biological function of miR-181c-5p in cervical squamous cell carcinoma (SCC) have not been well elucidated. MATERIALS AND

methodsSiHa cell lines with specific gene overexpression vectors were constructed. Targetscan was used to predict the binding site of miR-181c-5p and

results

conclusionTaken together, miR-181c-5p was able to mitigate the cancer cell characteristic and invasive properties of cervical SCC through targeting

Indexed as

apoptosiscancer stem cellepithelial-mesenchymal transitionkinase 3β interaction proteinmiR-181c-5p

Identifiers

PMID32547080
PMCPMC7247609
OpenAlexW3028267622

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.