Evidence map›Paper›PMID 32547607›Full record

ArticleJournal of geriatric cardiology : JGC2020

Long-term follow-up of antithrombotic management patterns in patients with acute coronary syndrome in China.

Xiao-Ning Han, Shu-Bin Qiao, Jun-Bo Ge, Ya-Ling Han, Ji-Yan Chen, Zu-Yi Yuan, Bo Yu, Jie Jiang, Yong Huo

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric cardiology : JGC, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Xiao-Ning HanDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Shu-Bin QiaoNational Center for Cardiovascular Diseases, Fuwai Hospital, Beijing, China.
Jun-Bo GeDepartment of Cardiology, Zhongshan Hospital Affiliated to Fudan University, Guangzhou, China.
Ya-Ling HanDepartment of Cardiology, the General Hospital of Shenyang Military, Shenyang, China.
Ji-Yan ChenDepartment of Cardiology, Guangdong General Hospital, Guangzhou, China.
Zu-Yi YuanDepartment of Cardiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Bo YuDepartment of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Jie JiangDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Yong HuoDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Peking University First Hospital · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNFu Wai Hospital · CNGuangdong General Hospital · CNPeking University · CNSecond Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the long-term antithrombotic management patterns (AMPs) and clinical outcomes of Chinese patients with acute coronary syndrome (ACS).

methodsThis was an observational, multicenter, longitudinal cohort extension study of Chinese patients who had completed the EPICOR Asia 2-year follow-up study post-hospitalization for an ACS event. Changes in AMP and clinical outcomes for up to 5 years post-ACS event were evaluated.

resultsOverall, 2334 patients with ACS were enrolled at 49 sites. The mean age was 61.6 years and 76.3% were men. By study end, 2093 patients completed the 3-year follow-up. At baseline (2 years post-ACS event), 72.4% of patents received one antiplatelet (AP) medication, with aspirin being the preferred one. A small proportion of patients (21.5%) was treated with two or more APs (2+ AP), and even fewer patients (6.1%) did not receive any AP medication at baseline. Upon study completion, the proportion of patients without AP therapy increased to 13.6%, while the percentage of patients on one AP and 2+ AP decreased to 69.3% and 17.1%, respectively. Numerically, a higher incidence of clinical events (composite of all-cause mortality, myocardial infarction, stroke) was observed for the 2+ AP (13.2%) subgroup than for the no AP (10.5%) and one AP (8.6%) subgroups. Furthermore, the 2+ AP subgroup exhibited the greatest number of bleeding events, outpatient visits, and hospitalization rates. Unlike myocardial infarction or stroke, bleeding events prompted an adjustment in AMP.

conclusionMost patients in China received at least one AP medication up to 5 years after an ACS event.

Indexed as

Acute coronary syndromeAntithrombotic agentsAntithrombotic management patternsObservational studyReal-world

Identifiers

PMID32547607
PMCPMC7276310
OpenAlexW3030949794

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.