Interrogation of the cell wall integrity pathway in

Tim M van Leeuwe, Mark Arentshorst, Peter J Punt, Arthur F J Ram

Open access · hybridAbstract read

In one paragraph

Article in Gene: X, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

0.6field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids inJournal of fungi (Basel, Switzerland) · 2023
Article
The cell wall and the response and tolerance to stresses of biotechnological relevance in yeasts.Frontiers in microbiology · 2022
Review
Deletion of theMicroorganisms · 2020
Article

4 · The record

Corrections and comments

Reprinted as
Interrogation of the cell wall integrity pathway in Aspergillus niger identifies a putative negative regulator of transcription involved in chitin deposition.2020

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tim M van LeeuweLeiden University, Institute of Biology Leiden, Molecular Microbiology and Biotechnology, Sylviusweg 72, 2333 BE Leiden, the Netherlands.

Mark ArentshorstLeiden University, Institute of Biology Leiden, Molecular Microbiology and Biotechnology, Sylviusweg 72, 2333 BE Leiden, the Netherlands.

Peter J PuntLeiden University, Institute of Biology Leiden, Molecular Microbiology and Biotechnology, Sylviusweg 72, 2333 BE Leiden, the Netherlands.

Arthur F J RamLeiden University, Institute of Biology Leiden, Molecular Microbiology and Biotechnology, Sylviusweg 72, 2333 BE Leiden, the Netherlands.

Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-fermentation fungal biomass waste provides a viable source for chitin. Cell wall chitin of filamentous fungi, and in particular its de-

Indexed as

5′-FOA, 5-fluoorotic acidBYE1 orthologueCell wall integrity pathwayCFW, CalcoFluor WhiteChitinCRISPR/Cas9CWI, cell wall integrityCWS, cell wall stressDR, direct repeatDSB, double strand breakGFP, green fluorescent proteinhygB, Hygromycin B resistance cassetteindel, insertion or deletionkusA, ku70 orthologue Aspergillus nigernicB, nicotinate mononucleotide pyrophosphorylase (nicotinamide synthesis)PAM, protospacer adjacent motifParasexual crossPHD, plant homeo domainpyrG, Orotidine-5′-phosphate decarboxylase (uracil synthesis)RNAPII, RNA polymerase IIsgRNA, single guide RNASNP, single nucleotide polymorphismSpen, split endsSPOC, spen paralogue and orthologue c-terminalTFIIS, transcription elongation factor S-IITranscriptional repressor

Identifiers

PMID32550555

DOI10.1016/j.gene.2020.100028

PMCPMC7285910

OpenAlexW3030902950

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.