ArticleMolecular plant pathology2020
Infection cushions of Fusarium graminearum are fungal arsenals for wheat infection.
Article in Molecular plant pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 65 citations in OpenAlex.
- A conserved fungal Egh16-like effector suppresses host defense by disrupting ATP binding of wheat MPK3.Journal of integrative plant biology · 2026Article
- Empowering fungal infection research with single-cell RNA sequencing.Communications biology · 2026Review
- Mechanism of Virulence in Fungal Pathogens with Diverse Modes of Living.Current microbiology · 2026Review
- Molecular Strategies and Regulatory Networks in the Early Infection Stages of Plant Pathogenic Fusarium Species.The plant pathology journal · 2026Review
- Regulator of G-Protein Signalling Protein AaRgs2 Negatively Regulates Appressorium-Like Formation of Alternaria alternata Induced by Pear Cutin Monomer via the AaRgs2-AaGα1-AaAC Module.Molecular plant pathology · 2026Article
- Comparative transcriptomics reveal contrasting strategies between a fungal plant pathogen and an endophyte during initial host colonization.Microbiology spectrum · 2025Article
- The Mgv1-Rlm1 axis orchestrates SAGA and SWI/SNF complexes at target promoters.Nucleic acids research · 2025Article
- Proteomic Analysis of theJournal of fungi (Basel, Switzerland) · 2025Article
- Identification and Confirmation of Virulence Factor Production fromJournal of fungi (Basel, Switzerland) · 2024Article
- Identification of Pathogen Causing Bulb Rot inPlants (Basel, Switzerland) · 2024Article
- Re-routing MAP kinase signaling for penetration peg formation in predator yeasts.PLoS pathogens · 2024Article
- Update on the Basic Understanding ofPlants (Basel, Switzerland) · 2024Review
- Advances in UnderstandingGenes · 2024Review
- Non-ribosomal peptide synthetase (NRPS)-encoding products and their biosynthetic logics in Fusarium.Microbial cell factories · 2024Review
- Multi-Omics Approaches Provide New Insights into the Identification of Putative Fungal Effectors fromMicroorganisms · 2024Article
- Genome-Wide Characterization of the RNA Exosome Complex in Relation to Growth, Development, and Pathogenicity of Fusarium graminearum.Microbiology spectrum · 2023Article
- Deoxynivalenol accumulation and detoxification in cereals and its potential role in wheat-aBIOTECH · 2023Review
- Article
- Appressoria-Small but Incredibly Powerful Structures in Plant-Pathogen Interactions.International journal of molecular sciences · 2023Review
- Comparative transcriptomics identifies the keyFrontiers in genetics · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fusarium graminearum is one of the most destructive plant pathogens worldwide, causing fusarium head blight (FHB) on cereals. F. graminearum colonizes wheat plant surfaces with specialized unbranched hyphae called runner hyphae (RH), which develop multicelled complex appressoria called infection cushions (IC). IC generate multiple penetration sites, allowing the fungus to enter the plant cuticle. Complex infection structures are typical for several economically important plant pathogens, yet with unknown molecular basis. In this study, RH and IC formed on the surface of wheat paleae were isolated by laser capture microdissection. RNA-Seq-based transcriptomic analyses were performed on RH and IC and compared to mycelium grown in complete medium (MY). Both RH and IC displayed a high number of infection up-regulated genes (982), encoding, among others, carbohydrate-active enzymes (CAZymes: 140), putative effectors (PE: 88), or secondary metabolism gene clusters (SMC: 12 of 67 clusters). RH specifically up-regulated one SMC corresponding to aurofusarin biosynthesis, a broad activity antibiotic. IC specifically up-regulated 248 genes encoding mostly putative virulence factors such as 7 SMC, including the mycotoxin deoxynivalenol and the newly identified fusaoctaxin A, 33 PE, and 42 CAZymes. Furthermore, we studied selected candidate virulence factors using cellular biology and reverse genetics. Hence, our results demonstrate that IC accumulate an arsenal of proven and putative virulence factors to facilitate the invasion of epidermal cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.