Evidence map›Paper›PMID 32575603›Full record

ReviewMedicina (Kaunas, Lithuania)2020

Risk Factors and Management of Osteoporosis Post-Transplant.

Karthik Kovvuru, Swetha Rani Kanduri, Pradeep Vaitla, Rachana Marathi, Shiva Gosi, Desiree F Garcia Anton, Franco H Cabeza Rivera, Vishnu Garla

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Bisphosphonates for osteoporosis in people with cystic fibrosis.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Article
  4. Article
  5. Review
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  8. Results of the implementation of a multidisciplinary care protocol for preventing fragility fractures following liver transplantation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Karthik KovvuruDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.
Swetha Rani KanduriDivision of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.ORCID 0000-0002-7190-6665
Pradeep VaitlaDivision of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.ORCID 0000-0001-5234-6722
Rachana MarathiDivision of Hospital Medicine, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.
Shiva GosiDepartment of Hospital Medicine, Banner Thunderbird Medical Center, Glenadale, AZ 85306, USA.
Desiree F Garcia AntonDivision of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.
Franco H Cabeza RiveraDivision of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39156, USA.
Vishnu GarlaDepartment of Internal Medicine and Mississippi Center for Clinical and Translational Research, University of Mississippi Medical Center, Jackson, MS 39156, USA.
University of Mississippi Medical Center · USBanner Thunderbird Medical Center · USJackson Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and mineral disorders are common after organ transplantation. Osteoporosis post transplantation is associated with increased morbidity and mortality. Pathogenesis of bone disorders in this particular sub set of the population is complicated by multiple co-existing factors like preexisting bone disease, Vitamin D deficiency and parathyroid dysfunction. Risk factors include post-transplant immobilization, steroid usage, diabetes mellitus, low body mass index, older age, female sex, smoking, alcohol consumption and a sedentary lifestyle. Immunosuppressive medications post-transplant have a negative impact on outcomes, and further aggravate osteoporotic risk. Management is complex and challenging due to the sub-optimal sensitivity and specificity of non-invasive diagnostic tests, and the underutilization of bone biopsy. In this review, we summarize the prevalence, pathophysiology, diagnostic tests and management of osteoporosis in solid organ and hematopoietic stem cell transplant recipients.

Indexed as

AgedBody Mass IndexBone DensityCigarette SmokingDisease ManagementFemaleHeart TransplantationHematopoietic Stem Cell TransplantationHumansImmobilizationKidney TransplantationLiver TransplantationLung TransplantationMaleOrgan TransplantationOsteoporosisSteroidsbone diseasekidney transplantliver transplantorgan transplantationosteoporosis

Identifiers

PMID32575603
PMCPMC7353876
OpenAlexW3036599083

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.