Evidence map›Paper›PMID 32582291›Full record

ArticleFrontiers in genetics2020

Genome-Wide Detection of CNVs and Association With Body Weight in Sheep Based on 600K SNP Arrays.

Zhipeng Wang, Jing Guo, Yuanyuan Guo, Yonglin Yang, Teng Teng, Qian Yu, Tao Wang, Meng Zhou, Qiusi Zhu, Wenwen Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Zhipeng WangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Jing GuoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Yuanyuan GuoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Yonglin YangState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Teng TengInstitute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
Qian YuState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Tao WangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Meng ZhouCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Qiusi ZhuCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Wenwen WangDepartment of Animal Genetics and Breeding, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China.
Qin ZhangDepartment of Animal Genetics and Breeding, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China.
Hua YangState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Northeast Agricultural University · CNXinjiang Academy of Agricultural and Reclamation Science · CNEducation Department of Heilongjiang Province · CNShandong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copy number variations (CNVs) are important genomic structural variations and can give rise to significant phenotypic diversity. Herein, we used high-density 600K SNP arrays to detect CNVs in two synthetic lines of sheep (DS and SHH) and in Hu sheep (a local Chinese breed). A total of 919 CNV regions (CNVRs) were detected with a total length of 48.17 Mb, accounting for 1.96% of the sheep genome. These CNVRs consisted of 730 gains, 102 losses, and 87 complex CNVRs. These CNVRs were significantly enriched in the segmental duplication (SD) region. A CNVR-based cluster analysis of the three breeds revealed that the DS and SHH breeds share a close genetic relationship. Functional analysis revealed that some genes in these CNVRs were also significantly enriched in the olfactory transduction pathway (oas04740), including members of the OR gene family such as

Indexed as

body weightbreed-specificcopy number variationsheepSNP

Identifiers

PMID32582291
PMCPMC7297042
OpenAlexW3035718042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.